Literature Search

Muellner(Markus K),Mair(Barbara),Ibrahim(Yas… Mol Syst Biol 2016-09-30

...SYK) as a novel and unexpected target in TNBC. Quantitative phosphoproteomics revealed that SYK inhibition abrogates sig...

Kim(Do-Hyun),Lee(Yong-Gab),Park(Hong-Jai),Le… Int Immunopharmacol 2016-01-04

...Syk inhibitor, in T cell activation, proliferation, and differentiation using isolated murine splenic T cells from C57BL...

Wang(Su Bin),Jang(Ji Yong),Chae(Yun Hee),Min… Free Radic Biol Med 2016-03-14

...Syk, Vav1, Btk, and PLCγ2) of collagen receptor signaling pathways was suppressed by kaempferol. Kaempferol also attenua...

Isayeva(Tatyana),Xu(Jie),Ragin(Camille),Dai(… Mod Pathol 2016-02-24

...Syk might increase MUC1 phosphorylation, leading to the observed decreased MMP1 expression.

LaRocca(T J),Stivison(E A),Mal-Sarkar(T),Hoo… Cell Death Dis 2016-02-18

...Syk-dependent induction of vesiculated morphology (echinocytes) that was associated with phosphorylation of Band 3 and w...

Joo(Hae Mi),Kang(Su Jin),Nam(Seon Young),Yan… PLoS One 2016-06-09

...Syk, phospholipase Cγ, and protein kinase C, as well as the intracellular free Ca2+ concentration ([Ca2+]i). The phospho...

Thoma(Gebhard),Veenstra(Siem),Strang(Ross),B… Bioorg Med Chem Lett 2016-06-17

...Syk inhibitor 5, which was found to be active in a rat PK/PD model. Compound 5 showed acceptable overall kinase selectiv...

Takahashi(Kenji),Hirose(Yusaku),Kamimura(Nao… Appl Environ Microbiol 2016-08-15

Sphingobium sp. strain SYK-6 is able to degrade various lignin-derived biaryls, including a phenylcoumaran-type compound...

Peter(B),Winter(G E),Blatt(K),Bennett(K L),S… Leukemia 2016-07-22

...SYK was recognized by both metabolites. Together, our data show that the clinically relevant midostaurin metabolite CGP5...

Choi(H-J),Park(S-Y),Cho(J H),Park(J-W),Sohn(… Allergy 2016-11-09

...Syk, which leads to phosphorylation of PLCγ and membrane translocation of PKCα. p38 MAPK is then activated by PKCα and s...