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Bioinformatics analysis of molecular mechanisms of chronic obstructive pulmon...

Chen(W),Hong(Y-Q),Meng(Z-L) Eur Rev Med Pharmacol Sci 2015-08-24

...SOCS3 were directly participated in this pathway. Furthermore, the DEGs of SOCS3, IL4, IL18R1, IL1R1, and IL6 were parti...

Qing Hua Chang Yin inhibits the LPS-induced activation of the IL-6/STAT3 sign...

Ke(Xiao),Hu(Guanghong),Fang(Wenyi),Chen(Ji... Int J Mol Med 2015-12-01

...SOCS3). Therefore, modulating the signaling feedback loop of IL-6/STAT3/SOCS3 may prove to be a novel therapeutic approa...

Significance of suppressor of cytokine signaling-3 expression in bladder urot...

Gaballah(Hanaa Hibishy),Shafik(Noha Mohame... Asian Pac J Cancer Prev 2015-10-01

...SOCS3 mRNA expression levels were evaluated using quantitative real time PCR. Urinary levels of interleukins 6 and 8 wer...

Inhibition of reactive oxygen species production ameliorates inflammation ind...

Ye(Siying),Lowther(Sue),Stambas(John) J Virol 2015-04-20

...SOCS3, enhancing negative regulation of cytokine signaling. These findings suggest that apocynin or its derivatives (tar...

Frequent SOCS3 and 3OST2 promoter methylation and their epigenetic regulation...

Chen(Haiyan),Zhang(Cuijuan),Sheng(Yan),Yao... Am J Cancer Res 2015-01-28

...SOCS3 and 3OST2 were the most frequently methylated genes in EC (88.3% and 78.3%, respectively), and 3OST2 was correlate...

Sex differences in the relationship of IL-6 signaling to cancer cachexia prog...

Hetzler(Kimbell L),Hardee(Justin P),Puppa(... Biochim Biophys Acta 2015-10-01

...SOCS3 mRNA expression as well as muscle IL-6r protein and STAT3 phosphorylation increased with severe cachexia in both s...

In vitro and in vivo conditional sensitization of hepatocellular carcinoma ce...

Minero(V G),De Stefanis(D),Costelli(P),Bac... Cell Cycle 2015-12-28

...SOCS3, c-FLIP and pSTAT3 were markedly downregulated. These observations provide a significant clue to critically improv...

High suppressor of cytokine signaling-3 expression impairs STAT3-dependent pr...

Xu(An Tao),Li(Yi),Zhao(Di),Shen(Jun),Xu(Xi... Inflamm Bowel Dis 2015-10-20

...SOCS3 expression were assessed with wounding assay and CCK-8 assay, respectively. Influence of STAT3 interference and SO...

Pioglitazone restores IGFBP-3 levels through DNA PK in retinal endothelial ce...

Thakran(Shalini),Zhang(Qiuhua),Morales-Tir... Invest Ophthalmol Vis Sci 2015-03-03

...SOCS3) levels. Numerous reports suggest prominent vasoprotective effects of insulin growth factor binding protein-3 (IGF...

Primordial follicle activation in the ovary of Ames dwarf mice.

Schneider(Augusto),Zhi(Xu),Moreira(Fabiana... J Ovarian Res 2015-10-13

...Socs3 was lower (P < 0.05) in older than younger N mice and not different (P > 0.05) between young and old df/df mice. T...

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