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[ABL1, SRC and other non-receptor protein tyrosine kinases as new targets for...

Klener(P),Klener(P) Klin Onkol 2010-10-12

...PDGFRB).Tyrosine kinase inhibitors (imatinib, nilotinib, dasatinib) now belong to established anti-cancer agents with cl...

Pericytes are required for blood-brain barrier integrity during embryogenesis...

Daneman(Richard),Zhou(Lu),Kebede(Amanuel A... Nature 2010-12-02

...Pdgfrb, which have defects in pericyte generation, we demonstrate that pericytes are necessary for the formation of the ...

The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination...

Toffalini(Federica),Kallin(Anders),Vandenb... Haematologica 2009-12-07

...PDGFRbeta (TPbeta, also called ETV6-PDGFRB) is a hybrid protein produced by the t(5;12) translocation, FIP1L1-PDGFRalpha...

Recent breakthroughs in the understanding and management of chronic eosinophi...

Lierman(Els),Cools(Jan) Expert Rev Anticancer Ther 2009-11-17

...PDGFRB), or FGF receptor 1 (FGFR1)'. In cases for which clonality is clear, but no PDGFRA, PDGFRB or FGFR1 rearrangement...

Isolation and culture of epithelial progenitors and mesenchymal stem cells fr...

Gargett(Caroline E),Schwab(Kjiana E),Zillw... Biol Reprod 2009-07-30

...PDGFRB (CD140B), MCAM (CD146) but not endothelial or hemopoietic markers PECAM1 (CD31), CD34, PTPRC (CD45). Adult human ...

Cross talk between hedgehog and epithelial-mesenchymal transition pathways in...

Ohta(H),Aoyagi(K),Fukaya(M),Danjoh(I),Ohta... Br J Cancer 2009-03-10

...PDGFRB, EDNRA, ROBO1, ROR2, and MEF2C) were found to be activated by an EMT regulator, SIP1/ZFHX1B/ZEB2, which was a tar...

t(3;21)(q22;q22) leading to truncation of the RYK gene in atypical chronic my...

Micci(Francesca),Panagopoulos(Ioannis),Hau... Cancer Lett 2009-05-07

...PDGFRB, JAK2, and ABL. We present a case of aCML with a 3q22;21q22-translocation that led to truncation of the receptor-...

Gene expression profiles reflect sclerosing cholangitis activity in abcb4 (-/...

Nakken(Karl E),Nygard(Stale),Haaland(Teres... Scand J Gastroenterol 2009-06-23

...Pdgfrb, Col1a1, Col1a2 and Col4a1 genes paralleled the unequal SC activities of CA- and UDCA-fed abcb4 (-/-) mice.,The n...

Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated a...

Walz(Christoph),Haferlach(Claudia),Hänel(A... Genes Chromosomes Cancer 2009-07-16

Chromosomal aberrations of 5q31-33 associated with rearrangements of the platelet-derived growth factor receptor beta (P...

Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1...

Chase(A),Schultheis(B),Kreil(S),Baxter(J),... Leukemia 2009-03-02

...PDGFRB gene fusions; however, occasional imatinib-responsive patients have been reported without abnormalities of these ...

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