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Functional comparison of human adenomatous polyposis coli (APC) and APC-like ...

Schneikert(Jean),Vijaya Chandra(Shree Hars... PLoS One 2014-02-07

...APC2). RNA interference revealed that it controls the level and/or the activity of β-catenin, but it is less efficient a...

Regulation of nuclear envelope dynamics via APC/C is necessary for the progre...

Aoki(Keita),Shiwa(Yuh),Takada(Hiraku),Yosh... Genes Cells 2014-02-20

...apc2 mutant, a mutation of Oar2, which was a 3-oxoacyl-[acyl carrier protein] reductase, was obtained. The level of the ...

Drosophila-Cdh1 (Rap/Fzr) a regulatory subunit of APC/C is required for synap...

Wise(Alexandria),Schatoff(Emma),Flores(Jul... Int J Dev Neurosci 2014-06-27

...APC2, a ligase subunit of the APC/C complex has been shown to regulate synaptic bouton size and activity (van Roessel et...

Discs large links spindle orientation to apical-basal polarity in Drosophila ...

Bergstralh(Dan T),Lovegrove(Holly E),St Jo... Curr Biol 2014-04-30

...APC2, and basal integrins in epithelial spindle orientation, but the underlying mechanisms remain unclear. We show that ...

miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell ...

Emmrich(Stephan),Rasche(Mareike),Schöning(... Genes Dev 2014-05-29

...APC2 stabilizes active β-catenin and enhances Wnt signaling. By switching the balance between Wnt and TGFβ signaling, th...

Ca(2+) regulation of mitochondrial function in neurons.

Rueda(Carlos B),Llorente-Folch(Irene),Amig... Biochim Biophys Acta 2014-10-09

...APC2/Slc25a23, with S0.5 for Ca(2+) of 300nM and 3.4μM, respectively. The lack of SCaMC-3 results in a smaller Ca(2+)-de...

The actin-binding protein profilin is required for germline stem cell mainten...

Shields(Alicia R),Spence(Allyson C),Yamash... Development 2014-03-11

...APC2) rescued GSC loss in chic hypomorphs, suggesting an additive role of APC2 and F-actin in maintaining the adherens j...

The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin lig...

Hainline(Sarah G),Rickmyre(Jamie L),Neitze... Biol Open 2014-07-16

...APC2) mutant embryos, consistent with dMCPH1 being an APC substrate in vivo. Using a purified, reconstituted system, we ...

Improving mRNA 5' coding sequence determination in the mouse genome.

Piovesan(Allison),Caracausi(Maria),Pelleri... Mamm Genome 2014-11-24

...Apc2 and Mknk2 cDNAs. We also generated a list of 16,330 mouse mRNAs where the presence of an in-frame stop codon upstre...

APC2 and Axin promote mitotic fidelity by facilitating centrosome separation ...

Poulton(John S),Mu(Frank W),Roberts(David ... Development 2013-12-11

...APC2, revealing that APC2 functions at the embryonic cortex with several protein partners, including Axin, to promote mi...

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