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Reported DNA repair protein CECR2, which is associated with neural tube defects…

Elliott(J),Norton(KA),Niri(FH),McDermid(HE) DNA Repair (Amst) 2020-00-00

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Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic…

Kooistra(MK),Leduc(RY),Dawe(CE),Fairbridge(N… Physiol Genomics 2012-01-18

...Cecr2, the cranial NTD exencephaly shows strain-specific differences in penetrance, with 74% penetrance in BALB/cCrl and...

Implantation failure and embryo loss contribute to subfertility in female mice …

Norton(KA),Niri(F),Weatherill(CB),Williams(C… Biol Reprod 2021-00-01

...Cecr2GT/GT and Cecr2GT/Del dams show defects in pregnancy. Cecr2GT/GT females have a normal number of implantation sites...

Elevated H3K79 homocysteinylation causes abnormal gene expression during neural…

Zhang(Q),Bai(B),Mei(X),Wan(C),Cao(H),Dan Li,… Nat Commun 2018-00-24

...Cecr2, Smarca4, and Dnmt3b. In human NTDs brain tissues, decrease in expression of CECR2, SMARCA4, and DNMT3B is also de...

Divide and Conquer. Pocket-Opening Mixed-Solvent Simulations in the Perspective…

Sabanés Zariquiey(F),Jacoby(E),Vos(A),van Vl… J Chem Inf Model 2022-00-14

...CECR2 bromodomain, TEM-1, and MCL-1. We compare previous experimental and computational findings to our results. It is s...

Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 …

Davidson(CE),Li(Q),Churchill(GA),Osborne(LR)… Physiol Genomics 2007-10-22

...Cecr2 mutation on a BALB/c background causes exencephaly at a frequency of 74% compared with 0% on an FVB/N background. ...

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.

Fedorov(O),Lingard(H),Wells(C),Monteiro(OP),… J Med Chem 2014-01-23

...CECR2, and CREBBP. This new series of compounds is the first example of submicromolar inhibitors of bromodomains outside...

Prenatal detection and characterization of a small supernumerary marker chromos…

Lin(CC),Hsieh(YY),Wang(CH),Li(YC),Hsieh(LJ),… Prenat Diagn 2006-10-00

...CECR2 and CECR7), did not reveal any hybridization signal with the marker chromosome. The karyotype of the fetus was 47,...

Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomai…

Romero(FA),Taylor(AM),Crawford(TD),Tsui(V),C… J Med Chem 2016-02-25

...CECR2, SMARCA4, and BAZ2A/B. Such novel inhibitors can be used to probe the physiological function of these non-BET brom...

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Hist…

Flynn(EM),Huang(OW),Poy(F),Oppikofer(M),Bell… Structure 2015-10-06

...CECR2, and the second bromodomain of TAF1 also recognize the longer butyryl mark. In addition, the TAF1 second bromodoma...

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