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Single-cell sequencing uncovers clonal dynamics profiles and therapeutic resi...

Zhang(N),Yu(J),Liu(H),Hu(Z),Meng(S),Sun(C)... Front Immunol None

...CSF1R interactions were also observed following combination treatment with chidamide and azacitidine. This study delinea...

Integrative transcriptomics, machine learning, and molecular docking derive a...

Wang(Y),Cai(M) Comput Biol Chem 2026-10-00

...CSF1R and TGF-β pathway inhibitors, and molecular docking simulations provide structural support for candidate drug-targ...

Predicting target interactomes and prognostic biomarkers of Quizartinib in ac...

Hebballi(AP),Hampannavar(GA),Gatibyali(I),... Comput Biol Chem 2026-07-18

...CSF1R, KIT, FLT3, PDGFRA, PDGFRB, NTRK1, ABL1, LYN, FLT1, and KDR. Survival analysis identified LYN, FLT3, and PDGFRA as...

Targeting the MAPK/ERK signaling pathway: Mechanistic analysis of pexidartini...

Peng(R),Zhan(Y),Cheng(Z),Li(A),Zhou(Y),Li(... Exp Cell Res 2026-09-01

...CSF1R inhibitor pexidartinib potently inhibited adriamycin-resistant MCF-7/ADR cells with a much lower IC50 than parenta...

CSF1R+ Macrophages and Osteoclasts Are Essential for Limb Bone Development Du...

Ma(F),Zhou(RRJ),Rosin(M),Rosin(JM) J Dev Biol 2026-07-08

...CSF1R inhibitor PLX5622 to pregnant mice across gestation to examine how CSF1R disruption impacts embryonic limb develop...

Secreted protein circuits in the gastrointestinal tumour microenvironment: de...

Li(K),Qian(Z),Mao(J),Han(Y),Leng(X) J Transl Med 2026-09-11

...CSF1R, IL-6-family cytokines, SPP1/osteopontin, periostin, galectins, DKK1, MIF, complement and soluble or vesicular PD-...

Rational Design and Optimization of Highly Selective CSF1R Inhibitors for the...

Yuan(X),Liu(K),Zou(Y),Wei(Y),Liu(Q),Zheng(... J Med Chem 2026-05-14

...CSF1R) is a key regulator of macrophage-driven liver inflammation. Here, we report a series of CSF1R inhibitors discover...

Differentiation of mesenchymal stem/stromal cells into CD45+ macrophage-like ...

Rusch(RM),Mabuchi(Y),Morikawa(S),Ogawa(Y),... iScience 2026-03-20

...CSF1R (also known as CD115) expression. Further analysis showed that PαS cells cultured in macrophage differentiation me...

CSF-1R inhibition and lenalidomide synergize to promote myeloma control after...

Minnie(SA),Ho(K),Boiko(JR),Adams(RC),Ensbe... Blood 2026-06-04

...Csf1r+ macrophages. Cell-cell communication analyses identified Csf1r+ macrophages as suppressors of these NK- and effec...

Single-cell analysis reveals the role of interleukins in impairing osteogenic...

Zhang(Z),Yang(X),Wang(C),He(J),Fang(Q),Zhu... Clin Exp Rheumatol 2026-05-13

...CSF1R axis between osteogenic MSCs and monocytes in OP. Diagnostic analysis further indicated high diagnostic value of I...

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