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Mobile elements in pituitary neuroendocrine tumors: integrative evidence and ...

Batista(RL),D'Alessandre(NDR),Craveiro(FL)... Endocr Relat Cancer 2026-05-01

...DAXX deficiency and TP53 inactivation, both established repressors of retroelements. Furthermore, the retrocopy-derived ...

Distinct DAXX effector modules separate H3.3 nucleosome assembly from ERV sil...

Jain(AY),Hoelper(D),Rashoff(AQ),Lewis(PW) bioRxiv 2026-03-23

...DAXX-bound ERVs in cells. Despite failure to deposit H3.3, DAXX with substitutions in this basic patch retains localizat...

DAXX in Metabolic, Aging, and Immune Regulation: Recent Insights.

Zhou(J),Zhao(L),Tuo(Q) Cells 2026-02-27

Death domain-associated protein 6 (DAXX) was originally identified as a key regulator of Fas receptor-mediated apoptosis...

Building a diagnostic scoring system for high-grade neuroendocrine neoplasms ...

Kinowaki(Y),Wang(C),Fukumura(Y),Ganci(M),Z... Am J Clin Pathol 2026-03-03

...DAXX/ATRX loss (-1), and somatostatin receptor subtype 2A 3+ (-1). In validation, the average score for PanNEC was 9.52 ...

An Integrative RNA Spliceosomic Landscape of Pancreatic Neuroendocrine Tumors...

Blázquez-Encinas(R),García-Vioque(V),Maffi... Endocr Pathol 2026-07-09

...DAXX/ATRX genes; in contrast, SPN3 was composed mainly by low grade tumors with beta-cell marker expression and the lowe...

Somatic Genetic Alterations in Pituitary Neuroendocrine Tumors.

Schwarz(Y),Halperin(R),Tirosh(A) Endocr Relat Cancer 2026-08-07

...DAXX, are enriched in aggressive corticotroph tumors. Identification of new molecular markers and delineation of their c...

Microglia activation by derepression of endogenous retroviruses drives inflam...

Yan(X),Georgopoulou(C),Lee(HM),Ahrari(A),R... Nat Neurosci 2026-08-17

...DAXX, a histone chaperone and RTE repressor, is downregulated during aging, preserves microglia homeostasis and inhibits...

PSIP1::TBL1X: a recurrent gene fusion in pancreatic neuroendocrine tumors.

Ackerman(D),Seyferth(ER),Li(W),Youngman(JE... Endocr Relat Cancer 2026-08-27

...DAXX mutations, defining a distinct molecular subgroup of pNETs. This study highlights the importance of structural vari...

Daxx-Dependent H3.3 Deposition Promotes Double-Strand Breaks Repair by Homolo...

Zannini(L),Aliprandi(S),Delia(D),Buscemi(G... Cells 2026-01-16

...DAXX plays a fundamental role in the response to DSBs. Indeed, in human cells, DSBs induce ATM/ATR-dependent phosphoryla...

UBA52 Overexpression Ameliorates Intracerebral Hemorrhage-Associated Neuronal...

Ma(S),Liu(Q),Han(W),Liu(Z),Jin(S),Wu(H),Hu... Mol Neurobiol 2026-01-19

...Daxx as a UBA52-interacting protein, with UBA52 promoting Daxx ubiquitination and degradation. Rescue experiments showed...

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