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Tagln1-Cre driven Ercc1 deficiency reveals sex specific effects on adipose ti...

Jüttner(AA),Delhanty(PJD),Raben(JD),Goos(Y... Endocrinology 2026-09-16

...Ercc1 in mice (Tagln1-Cre Ercc1 mice) leads to accelerated aging of VSMC and perivascular adipocytes resulting in vascul...

Rad1-Rad10 uses different interfaces to interact with pathway-specific DNA re...

Rodríguez González(J),Herman(OT),Lewis(KE)... Nucleic Acids Res 2026-09-07

Saccharomyces cerevisiae Rad1-Rad10 (XPF-ERCC1 in humans) is a 3'-flap endonuclease with key roles in DNA repair. Pathwa...

Development of a predictive model for neutropenia risk in Japanese breast can...

Miyagi(T),Tsuji(D),Nakatani(E),Sahara-Ishi... Br J Clin Pharmacol 2026-01-00

...ERCC1 rs11615, ERCC2 rs238406 and XRCC3 rs709399. The model had an AUC of 0.744 (95% CI, 0.666-0.823), and including gen...

ERCC1/NGFR affects prognosis in basal-like breast cancer.

Lei(Y),Li(X),Fan(F),Feng(R),He(J),Zhong(J)... Eur J Med Res 2025-07-09

...ERCC1, and NGFR was associated with ERCC1.After knockdown of ERCC1, the migratory and invasive abilities of cancer cells...

Targeted inhibition of JMJD2C/MALAT1 axis compensates for the deficiency of m...

Li(L),Zhang(J),Li(H),Qin(L),Wu(H),Li(Z),Ca... Life Sci 2025-07-15

...ERCC1 signaling pathways, with their knockdown produced the opposite effect. Metformin increased JMJD2C expression in tu...

Association of the expression of 5-FU biomarkers with aging and prognosis in ...

Soh(J),Yamamoto(H),Okumura(N),Suzuki(H),Na... Mol Clin Oncol 2025-09-00

...ERCC1), were assessed via quantitative reverse-transcription PCR assays in 89 elderly patients (≥75 years) with NSCLC wh...

Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid ...

Gómez-Liñán(C),Sáez-Maldonado(M),Montosa-H... Sci Rep 2025-07-02

...ERCC1 endonuclease complex. Here, we identify an XPF ortholog in Trypanosoma brucei, the causative agent of human Africa...

A new multisystem ERCC1-hepatorenal syndrome: insights from a clinical cohort...

White(SM),Wondergem(AP),Breet(I),Dittmaier... Eur J Hum Genet 2025-10-00

...ERCC1-XPF is a multifunctional endonuclease involved in nucleotide excision repair (NER) and interstrand crosslink (ICL)...

Predictive Value of Tumor ERCC1 Expression for Treatment Outcomes After Adjuv...

Nakata(M),Saisho(S),Soh(J),Okumura(N),Naka... Cancer Manag Res 2025-00-00

...ERCC1 expression. There were no significant differences in the patient characteristics or OS between the tumor ERCC1-pos...

Glucose transporter protein 1-targeted polymetallic coordination nanopolymer ...

Zhang(W),Wang(X),Wang(P),Li(Q),Zhang(Y),Me... J Colloid Interface Sci 2025-12-15

...ERCC1), glutathione (GSH), and adenosine triphosphate (ATP), effectively disrupting DNA repair pathways, preventing CDDP...

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