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Circulating cochlin LCCL domain binds to dying cells and enhances efferocytosis.

Courcol(L),Hassan(A),Haftek-Terreau(Z),Vig... Cell Rep 2026-08-04

...GAS6. Our findings provide a role of cochlin LCCL domain in the regulation of efferocytosis, alongside its already descr...

ApoE impairs microglial efferocytosis by targeting Gas6/MerTK in a mouse mode...

Gao(B),Cheng(SM),Zhang(YY),Yang(HX),Hu(MM)... Acta Pharmacol Sin 2026-09-00

...Gas6/MerTK-dependent microglial efferocytosis. Furthermore, exogenous delivery of recombinant Gas6 had anti-seizure and ...

Microglial PICALM: A novel genetic driver and therapeutic target in vascular ...

Chai(Z),Xu(Q),Cheng(D),Zhang(Y),Liu(Z),Wan... Arch Gerontol Geriatr 2026-06-04

...GAS6, GRN). PheWAS revealed no pleiotropy. In silico drug repurposing prioritised three FDA-approved BBB-penetrant compo...

C3+ cancer-associated fibroblast-derived GAS6 promotes cervical cancer metast...

Zhan(J),Liu(D),Ye(J),Peng(X),Liu(X),Lu(W),... J Transl Med 2026-06-08

...GAS6/AXL pathway. This syngeneic orthotopic mouse model effectively replicates the metastatic cascade of cervical cancer...

CD301b+ tissue-resident macrophages drive bone repair as an early-responding ...

Zhou(X),Zeng(H),Qu(S),Li(J),Luo(X),Tan(K),... Int Immunopharmacol 2026-09-15

...Gas6 axes, recruiting macrophages and driving their transition toward pro-repair and osteogenic states. Functional studi...

Envelope protein residue E152 confers enhanced GAS6-dependent cell entry to t...

Kamiyama(N),Saechue(B),Watanabe(K),Chalala... Antiviral Res 2026-08-00

...GAS6), a ligand for AXL and other TAM receptor family members, thereby facilitating efficient cellular entry. These find...

Paeoniflorin elevates the expression of SOCS3 in macrophages to prevent MIA-i...

Sun(C),Bian(X),Qi(X),Qin(X),Fan(W),Tao(Z),... J Biomed Res 2026-06-25

...Gas6 expression, activated the Axl receptor, upregulated suppressor of cytokine signaling 3 (SOCS3) expression, inhibite...

LncRNA GAS6-AS1 enhances the progression of pediatric neuroblastoma by modula...

Chen(J),Huang(H),Lin(J),Xu(Y),Wu(Q) World J Surg Oncol 2026-05-29

...GAS6-AS1 expression levels in neuroblastoma tissues. The association between GAS6-AS1 expression and clinical features w...

TAM receptor-ligand interfaces in zebrafish and mammals: A comparative struct...

Torres Alegre(EO) J Struct Biol 2026-05-29

...Gas6 and Protein S are central regulators of phagocytosis and immune resolution in the nervous system, but whether intri...

Association of Serum AXL and Gas6 Levels with Clinical Outcomes in Non-Hodgki...

Wang(L),Zhang(Y),Guo(Y),Yang(M),Zi(Y),Liu(... Infect Drug Resist None

...Gas6 as independent risk factors for poor prognosis (P < 0.05). ROC curve analysis showed that AXL and Gas6 had robust p...

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