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Next-generation AI-assisted drug design against cancer: large language models...

Khanehzar(E),Shams(F),Jafari(A),Poustforoo... In Silico Pharmacol None

...GAS6 pathway promotes tumor growth, invasion, metastasis, and resistance to apoptosis. Large Language Models (LLMs) can ...

Oleanolic acid alleviates stress-induced alopecia via modulating brain-skin a...

Han(B),Wang(Y),Yang(Z),Chen(Y),Huang(X),Zh... Phytomedicine 2026-07-25

...GAS6. Furthermore, in vitro studies demonstrated that OA mitigated corticosterone-induced ferroptosis-like changes (rest...

A systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RE...

Chan(M),Zhu(S),Russell(ZR),Arora(S),Arakak... Proc Natl Acad Sci U S A 2026-02-17

...GAS6, and MERTK inhibition led to suppression of pro-survival signaling pathways including MEK/ERK (Mitogen-Activated Pr...

First-Trimester Maternal Serum Growth Arrest-Specific Protein 6 (Gas6) Levels...

Yılmaz(Z),Yurtcu(N),Karademir(D),Calıskan(... J Clin Med 2026-07-17

...Gas6), a vitamin K-dependent ligand for the TAM receptor family (Tyro3, AXL, and MerTK), is crucial for trophoblast inva...

Receptor-Ligand Biomarker Profile in Ankylosing Spondylitis: Associations Bet...

Dogan(SC),Zontul(C),Atas(M),Ozmen(E),Kaya(... Life (Basel) 2026-06-26

...GAS6), and Protein S, is a key regulator of immune homeostasis. This study investigated these receptor-ligand components...

Altered Gas6/sMerTK Balance in Gingival Crevicular Fluid Across Periodontal H...

Ercan(N),Meracı Yıldıran(B),Akgül(Z),Ateş ... J Clin Med 2026-06-28

...Gas6 total amount was higher in the diseased groups, whereas its concentration decreased. The Gas6/sMerTK ratio increase...

Advances, challenges, and innovative strategies of CAR-T cell therapy in panc...

Xiao(RY),Jiang(YF),Zhao(W),Wang(QQ),Huang(... Biomark Res 2026-08-07

...GAS6), and glypican-1 (GPC1), while also highlighting emerging next-generation CAR-T engineering strategies, including n...

GAS6 Mediates Benzo[a]pyrene-Induced Pathological Cardiac Hypertrophy via the...

Li(G),Long(F),Liu(Z),Fu(JN),Teng(Y),Cai(S)... Chem Biol Interact 2026-08-25

...GAS6) mediates BaP-induced cardiac remodeling. Target integration and Mendelian randomization analysis nominated GAS6 as...

Targeting Compensatory AKT Activation Overcomes Resistance to AXL Inhibition ...

Gao(H),Zhan(Y),Bao(M),Liu(C),Lan(T),Gao(H)... Mol Cancer Ther 2026-09-05

The GAS6/AXL pathway plays a crucial role in promoting tumor survival and therapy resistance in various cancers. However...

Rosa damascena-Derived Nanovesicles Restore GAS6-driven Efferocytic Balance i...

Brahadeeswaran(S),Tamizhselvi(R) J Drug Target 2026-09-04

...GAS6 expression in a dose-dependent manner, supporting enhanced efferocytosis and inflammation resolution. Western blott...

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