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Up-regulation of the inflammatory response by ovariectomy in collagen-induced a…

Ibáñez(Lidia),Alcaraz(Maria José),Maicas(Nur… Inflammation 2012-06-04

...hPGDS, PGD2, PGE2, and MMP-3 in joint tissues; and also decreased focal bone loss in the inflamed joint. Ovariectomy up-...

Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile iso…

Tippin(Brigette L),Levine(A Joan),Materi(Ali… Prostaglandins Other Lipid Me… 2012-08-23

...HPGDS, which is a glutathione transferase that forms prostaglandin D(2) (PGD(2)). We characterized naturally occurring H...

Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthas…

Gandhi(Ujjawal H),Kaushal(Naveen),Ravindra(K… J Biol Chem 2011-10-10

...Hpgds promoter suggesting a positive feedback mechanism of H-PGDS expression. Alternatively, the expression of nuclear f...

Comprehensive expression analysis of prostanoid enzymes and receptors in the hu…

Catalano(Rob D),Wilson(Martin R),Boddy(Sheil… Mol Hum Reprod 2011-06-23

...HPGDS, PTGDS, PTGIS, TBXAS1 and HPGD) and the prostanoid receptors (PTGER1, PTGER2, PTGER3, PTGER4, PTGFR, PTGDR, GPR44,...

Expression and detrimental role of hematopoietic prostaglandin D synthase in sp…

Redensek(Adriana),Rathore(Khizr I),Berard(Je… Glia 2011-06-30

...HPGDS) deficient mice and a HPGDS selective inhibitor (HQL-79), that PGD(2) plays a detrimental role after SCI. We also ...

Nettle extract (Urtica dioica) affects key receptors and enzymes associated wit…

Roschek(Bill),Fink(Ryan C),McMichael(Matthew… Phytother Res 2009-07-27

...HPGDS), central enzymes in pro-inflammatory pathways. The IC(50) value for histamine receptor antagonist activity was 25...

Inhibition of prostaglandin D synthase suppresses muscular necrosis.

Mohri(Ikuko),Aritake(Kosuke),Taniguchi(Hidet… Am J Pathol 2009-05-19

...HPGDS) appeared in necrotic muscle fibers from patients with either Duchenne muscular dystrophy or polymyositis. HPGDS i...

Protective role of hematopoietic prostaglandin D synthase in transient focal ce…

Liu(M),Eguchi(N),Yamasaki(Y),Urade(Y),Hattor… Neuroscience 2009-12-15

...HPGDS) after ischemic/reperfusion injury and its localization in microglia, but the molecular mechanism(s) of HPGDS acti...

Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregul…

Mohri(Ikuko),Kadoyama(Keiichi),Kanekiyo(Taka… J Neuropathol Exp Neurol 2007-07-17

Prostaglandin (PG) D2 is produced in activated microglia by the action of hematopoietic PGD synthase (HPGDS) and plays i...

Expression of prostaglandin D2 synthase in activated eosinophils in nasal polyp…

Hyo(Sawako),Kawata(Ryo),Kadoyama(Keiichi),Eg… Arch Otolaryngol Head Neck Su… 2007-09-13

...HPGDS) expression was examined by semiquantitative Western blot analysis and by immunohistochemical staining with anti-H...

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