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HPGDS

Gene name:hematopoietic prostaglandin D synthase

...HPGDS主要在造血系统中表达,特别是在肥大细胞、巨噬细胞和树突状细胞中高度活跃。HPGDS的突变可能导致其酶活性改变,进而影响PGD2的产生。PGD2水平异常与多种疾病相关,例如过敏性疾病(如哮喘和过敏性鼻炎)、自身免疫疾病和某些癌症。H...

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