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Comprehensive Integrated Analyses of Proteins and Metabolites in Equine Semin...

Wen(X),Bou(G),He(Q),Liu(Q),Yi(M),Ren(H) Proteomes 2025-07-04

...HSPG2 in the glycosaminoglycan biosynthesis signaling pathway; the metabolites D-glucose, 4-phosphopantetheine, and 4-hy...

Challenges in Genomic Variant Interpretation Within Pakistani Populations due...

Khalid(Z),Adams(M),Muhammad(A),Tehreen(R),... Am J Med Genet A 2025-12-00

...HSPG2, and ACOX3. Our studies highlight the challenges of rare variant interpretation within the Pakistani community, le...

Evolution of the perlecan/HSPG2 gene and its activation in regenerating Nemat...

Warren(Curtis R),Kassir(Elias),Spurlin(Jam... PLoS One 2016-01-11

The heparan sulfate proteoglycan 2 (HSPG2)/perlecan gene is ancient and conserved in all triploblastic species. Its pres...

A missense mutation in domain III in HSPG2 in Schwartz-Jampel syndrome compro...

Iwata(Satoshi),Ito(Mikako),Nakata(Tomohiko... Neuromuscul Disord 2016-03-21

...HSPG2 encoding perlecan. Six missense mutations have been reported in SJS to date and only one has been characterized us...

Perlecan heparan sulfate deficiency impairs pulmonary vascular development an...

Chang(Ya-Ting),Tseng(Chi-Nan),Tannenberg(P... Cardiovasc Res 2016-05-24

...Hspg2(Δ3/Δ3). At 4 weeks, FGF2 mRNA and protein were also significantly reduced in Hspg2(Δ3/Δ3) lungs. Ligand and carboh...

Balkan nephropathy.

Stefanovic(Vladisav),Toncheva(Draga),Polen... Clin Nephrol 2016-05-24

...HSPG2, and KCNK5) in BN patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, w...

DNA-PKcs plays role in cancer metastasis through regulation of secreted prote...

Kotula(Ewa),Berthault(Nathalie),Agrario(Ce... Cell Cycle 2016-04-19

...HSPG2 and the inhibitors of matrix metalloproteinases, such as α-2M and TIMP-2). High throughput analysis of secretomes,...

Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage D...

Shu(Cindy C),Jackson(Miriam T),Smith(Marga... Arthritis Rheumatol 2016-08-15

...Hspg2(Δ3-/Δ3-) mice (Hspg2 lacking domain 1 HS, generated by ablation of exon 3 of perlecan). Cartilage damage, subchond...

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumo...

Greening(David W),Lee(Sze Ting),Ji(Hong),S... Oncotarget 2016-09-06

...HSPG2). These findings correlated with western immunoblotting (xenograft lysates) and histological examination by immuno...

Proteoglycan expression correlates with the phenotype of malignant and non-ma...

Tsidulko(Alexandra Y),Matskova(Liudmila),A... Oncotarget 2016-10-11

...HSPG2. For Burkitt's lymphoma cells (BL), serglycin was down-regulated in BL type III cells and perlecan in type I BL ce...

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