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Tristetraprolin (TTP) coordinately regulates primary and secondary cellular res…

Qiu(Lian-Qun),Lai(Wi S),Bradbury(Alyce),Zeld… J Leukoc Biol 2015-06-11

...Ier3, Ptgs2, and Lif, were significantly slowed in TTP-deficient fibroblasts after TNF stimulation. These changes were a...

Expression of IER3 in primary hepatocarcinoma: correlation with clinicopatholog…

Liu(Zhong),Wang(Xin-Mei),Jia(Tong-Fu),Zhai(Y… Asian Pac J Cancer Prev 2015-12-14

...IER3) is involved in many biological processes. Recently, it was discovered that IER3 plays an important role in tumorig...

Pharmacologic stabilization of hypoxia-inducible transcription factors protects…

Trollmann(R),Richter(M),Jung(S),Walkinshaw(G… Neuroscience 2015-10-20

...IER3)) and migratory factors (chemokine receptor 4 (CXCR4), stromal cell-derived factor 1 (SDF-1)) was determined (quant...

Translational regulation of specific mRNAs controls feedback inhibition and sur…

Schott(Johanna),Reitter(Sonja),Philipp(Janin… PLoS Genet 2015-06-23

...Ier3 knockout mice showed reduced survival upon activation, indicating that IER3 induction protects macrophages from LPS...

IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ER…

Garcia(Maria Noé),Grasso(Daniel),Lopez-Milla… J Clin Invest 2015-03-02

...Ier3) as part of a prooncogenic transcriptional pathway. Here, we evaluated the role of IER3 in PanIN formation and PDAC...

Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through spe…

de Laval(Bérengère),Pawlikowska(Patrycja),Ba… Blood 2014-03-19

...ier3), upon DNA damage. Iex-1 forms a complex with pERK and the catalytic subunit of DNA-PK, which is necessary and suff...

T lymphocytes from chronic HCV-infected patients are primed for activation-indu…

Zhao(Bin-Bin),Zheng(Su-Jun),Gong(Lu-Lu),Wang… PLoS One 2014-06-24

...IER3 and BCL2A1 in CD8(+) T-cells from CHC patients as HCV-specific gene signatures. Importantly, the gene expression pa...

Stress-induced hematopoietic failure in the absence of immediate early response…

Ramsey(Haley),Zhang(Qi),Brown(Diane E),Steen… Haematologica 2014-07-24

...IER3) is diminished significantly in hematopoietic stem cells in a subgroup of patients with early stage myelodysplastic...

Quantitative and qualitative pleiotropic differences between Simvastatin single…

Sternberg(Zohara),Chichelli(Trevor),Sternber… Atherosclerosis 2014-07-28

...IER3, and CSF1R, and downregulated the expression levels of genes related to cellular proliferation, including PTN and C...

Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stres…

Stachel(Imke),Geismann(Claudia),Aden(Konrad)… J Biol Chem 2014-03-26

...IER3) has a crucial role under these conditions. We now demonstrate that colonic tissue from Ier3(-/-) mice subject of d...

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