...IER3, STAT3, SFRP1, PHLDA1, JAK2, MYC, S100A8) showed high diagnostic performance (AUC > 0.95). Two molecular subtypes d...
...IER3. SAA thus can act directly through specific transcription to alter cellular physiology in cells outside the monocyt...
...IER3/IEX-1) encodes a radiation-inducible stress-response adaptor protein that integrates pro-survival signaling pathway...
...IER3 upregulation. Clinical samples confirmed IER3 protein overexpression correlated with advanced grade (p < 0.001). In...
...IER3, TIMP1, TBX3, SEC61G) and TNBC (ADM, C4orf3, LDHA) tumors, as well as shared biomarkers (FN1, LOXL2, P4HA1). Multip...
...IER3, ATF4 and SLC19A2 as the top five ranking genes. The best-performing random forest model achieved an AUC of 0.664, ...
...IER3, IFNGR1, PLAUR, SERPINB8, and VNN2. The GO and KEGG enrichment analyses revealed that these genes participate in es...
...IER3, SOCS3, and NFKBIA. Incorporation of OpenTargets druggability data highlighted putative clinically tractable genes ...
...IER3 drives CRC proliferation, invasion, and metastatic capacity both in vitro and in vivo. Mechanistically, IER3 activa...
...IER3, UBD, TECPR1) and downregulation of antioxidant markers (PRDX2, SOD3, CAT, Nrf2), alongside sequence variations. Bi...
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