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Identification of PANoptosis-Related Biomarkers in Hypertrophic Cardiomyopathy:…

Zhong(J),Zhao(Q),Wu(R),Zhang(S),Liu(G),Zhang… J Inflamm Res None

...IER3, STAT3, SFRP1, PHLDA1, JAK2, MYC, S100A8) showed high diagnostic performance (AUC > 0.95). Two molecular subtypes d...

Serum Amyloid A (SAA) induces transcription affecting inflammation.

Sack(GH),Yun(J),Talbot(CC),Sethi(J) PLoS One None

...IER3. SAA thus can act directly through specific transcription to alter cellular physiology in cells outside the monocyt...

Lysophosphatidic Acid Receptor Activation Regulates Expression of the Immediate…

Norman(DD),Shin(Y),Balázs(L),Szabó(E),Benyó(… Radiat Res 2026-09-02

...IER3/IEX-1) encodes a radiation-inducible stress-response adaptor protein that integrates pro-survival signaling pathway...

IER3 as an RFX5 transcriptional co-activator promotes hepatocellular carcinoma …

Chen(X),Zhang(Q),Zhang(N) Discov Oncol 2026-05-28

...IER3 upregulation. Clinical samples confirmed IER3 protein overexpression correlated with advanced grade (p < 0.001). In...

Single-cell profiling reveals a novel CAF subpopulation linking stromal heterog…

Vigiano Benedetti(V),Conte(F),Santoni(D),Pen… J Transl Med 2026-06-25

...IER3, TIMP1, TBX3, SEC61G) and TNBC (ADM, C4orf3, LDHA) tumors, as well as shared biomarkers (FN1, LOXL2, P4HA1). Multip...

A Phase 1 Prognostic Trial for Predicting Paediatric Allergy Using the Placenta…

Clifton(VL),Saif(Z),Balbon(AP),Afnan(M),Tai(… Clin Exp Allergy 2026-07-00

...IER3, ATF4 and SLC19A2 as the top five ranking genes. The best-performing random forest model achieved an AUC of 0.664, ...

Integrated expression quantitative trait loci and Mendelian randomization analy…

He(P),Lv(X),Fu(C),Qin(Z),Chen(S),Zhao(J),Xie… Front Mol Biosci None

...IER3, IFNGR1, PLAUR, SERPINB8, and VNN2. The GO and KEGG enrichment analyses revealed that these genes participate in es...

Machine learning based prioritisation of genes associated with osteoarthritis j…

Soul(J),Young(DA) Osteoarthritis Cartilage 2026-03-00

...IER3, SOCS3, and NFKBIA. Incorporation of OpenTargets druggability data highlighted putative clinically tractable genes ...

IER3 Promotes Malignant Progression of Colorectal Cancer Through the NF-κB Path…

Wei(Z),Luo(Y),Zhang(Y),Huang(Q),Shao(J),Zhan… Int J Genomics None

...IER3 drives CRC proliferation, invasion, and metastatic capacity both in vitro and in vivo. Mechanistically, IER3 activa...

Integrative analysis of genetic, biochemical, and microbial factors in camel ca…

Elsayed(A),Hafez(AA),Ragab(MT),Fawzy(MA),El-… Vet Res Commun 2026-02-06

...IER3, UBD, TECPR1) and downregulation of antioxidant markers (PRDX2, SOD3, CAT, Nrf2), alongside sequence variations. Bi...

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