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The identification of loci for immune traits in chickens using a genome-wide ...

Zhang(Lei),Li(Peng),Liu(Ranran),Zheng(Maiq... PLoS One 2016-02-25

...IL4I1, CD1b, GNB2L1, TRIM27 and ZNF692) located in this region, changes in IL4I1, CD1b transcripts were consistent with ...

Human spermatozoa possess an IL4I1 l-amino acid oxidase with a potential role...

Houston(B),Curry(B),Aitken(R J) Reproduction 2016-02-02

...IL4I1), an l-amino acid oxidase (LAAO) which is capable of generating ROS on exposure to aromatic amino acids in the pre...

Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of T...

Kerbrat(Stéphane),Vingert(Benoit),Junier(M... PLoS One 2016-05-24

...IL4I1 was enhanced. Finally, a defective humoral response was shown in PEA-15-deficient mice in a model of red blood cel...

IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T C...

Yue(Yinpu),Huang(Wei),Liang(Jingjing),Guo(... PLoS One 2016-06-21

...IL4I1) was initially described as an early IL-4-inducible gene in B cells. IL4I1 protein can inhibit T cell proliferatio...

The immunosuppressive enzyme IL4I1 promotes FoxP3(+) regulatory T lymphocyte ...

Cousin(Céline),Aubatin(Aude),Le Gouvello(S... Eur J Immunol 2015-08-18

...IL4I1 on naïve CD4(+) T-cell differentiation. We show that IL4I1 stimulates the generation of Foxp3(+) regulatory T (Tre...

EpsinR, a target for pyrenocine B, role in endogenous MHC-II-restricted antig...

Shishido(Tatsuya),Hachisuka(Masami),Ryuzak... Eur J Immunol 2015-03-03

...IL4I1) by primary dendritic cells (DCs). Phage display screening and surface plasmon resonance (SPR) analysis were used ...

Differential expression of the immunosuppressive enzyme IL4I1 in human induce...

Scarlata(Clara-Maria),Celse(Clotilde),Pign... Eur J Immunol 2015-04-13

IL4I1 encodes an L-phenylalanine oxidase that inhibits T-cell proliferation. It has been recently reported that IL4I1 is...

Reasons for rarity of Th17 cells in inflammatory sites of human disorders.

Annunziato(Francesco),Santarlasci(Veronica... Semin Immunol 2014-07-18

...IL4I1), which encodes for a l-phenylalanine oxidase, that has been shown to down-regulate CD3ζ expression in T cells. Th...

IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR un...

Santarlasci(Veronica),Maggi(Laura),Mazzoni... Eur J Immunol 2014-05-09

...IL4I1) upregulation. Here, we show that in human Th17 cells, IL4I1 also maintains high levels of Tob1, a member of the T...

Antibacterial properties of the mammalian L-amino acid oxidase IL4I1.

Puiffe(Marie-Line),Lachaise(Isabelle),Moli... PLoS One 2013-06-24

...IL4I1) may also participate in the in vivo inhibition of staphylococci growth. Thus, IL4I1 plays a distinct role compare...

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