Tada(K),Mitsuyama(K),Nishizawa(H),Shima(H)... Gastro Hep Adv 2026-00-00

...MAT2A or its inhibitor cycloleucine. Furthermore, inhibitors of several enzymes in the polyamine biosynthetic pathway al...

Pirini(F),Ferrari(A),Jandoubi(M),Azzali(I)... Cell Death Discov 2025-07-02

...MAT2A), two enzymes at the crossroad between polyamine metabolism and protein methylation, in this review we examine and...

Flaherty(JN),Sivasudhan(E),Tegowski(M),Xin... Cell Rep 2025-07-22

...MAT2A regulation. Moreover, these cells are hypersensitive to treatment with a MAT2A inhibitor and to deletion of the MT...

Zhang(S),Li(J),Wang(Z),Jiao(Y),Shi(X),Ai(Y... Bioorg Chem 2025-09-00

...MAT2A. The inhibition of MAT2A SUMOylation unexpectedly stimulated polyamine synthesis. Lastly, we showed that the combi...

Sharma(B),Chauhan(V),Dhiman(VK),Kumar(R),M... 3 Biotech 2025-10-00

...MAT2A (- 895.1), and SAHH (- 890.9). These findings highlight the successful optimization of MGL production, its effecti...

Xia(C),Min(J) Oncol Lett 2025-12-00

...MAT2A may be tightly regulated by SAM through a feedback mechanism, ensuring homeostasis of the methionine-MAT2A-SAM met...

O'Leary(Valerie Bríd),Ovsepian(Saak Victor... Cell Rep 2016-01-26

...MAT2A promoter CpG island. We show that PARTICLE represses MAT2A via methylation and demonstrate that the radiation-indu...

Tomasi(Maria Lauda),Ryoo(Minjung),Ramani(K... Oncotarget 2016-09-22

...MAT2A expression are up-regulated in several malignancies. Exogenous SAMe decreases Ubc9 and MAT2A expression and is pro...

Zhang(Jian),Wang(Yan),Shang(Desi),Yu(Fulon... J Biomed Inform 2016-01-25

...MAT2A, CDKN1A, AREG, JUN) have the potentialities to become new targets for cancer therapy.

Ngai(Ying Fai),Sulistyoningrum(Dian C),O'N... Am J Physiol Regul Integr C... 2016-04-26

...Mat2a, Mthfr, and Cbs mRNA) and programming of HPA function genes (Nr3c1, Nr3c2, and Slc6a4) in offspring from ethanol-f...