...NRK-52E cells subjected to hypoxia-reoxygenation injury. Furthermore, in an RIRI mice model, 22f selectively activated r...
...NRK kidney cells. This integrative QSAR-docking-MD-FEL-MTT approach effectively identified compound 0356-0096 as a poten...
...NRK-49F cells at concentrations ranging from 0.5 to 5 μM. In vitro, MHH effectively suppressed TGF-β1-induced PAI-1 expr...
...NRK-52E) cells were cultured under hypoxic condition (1% O2) or normoxic condition. The expression of fibrotic markers a...
...NRK-52E cells. Animals were randomly assigned to the sham, UUO, and UUO + AMB (0.5 mg/kg, p.o., o.d.) groups for 21 days...
...NRK-52E) cells, we observed the emergence of resistant subpopulations and established two ferroptosis-resistant clones, ...
...NRK-52E cells. In vivo, Res (5-20 mg/kg) significantly improved renal function, alleviated histopathological damage, and...
...NRK-52E and NRK-49F cells, significantly attenuating TGF-β1-induced upregulation of fibronectin, collagen I, and α-SMA e...
...NRK-52e, NRK 49f, and HCK-8). RNA-seq analysis and target protein validation displayed that the anti-renal fibrosis acti...
...NRK-52E tubular cells and mice Raw 264.7 macrophages treated with ovalbumin immunocomplexes (OVA-IC) to mimic LN model i...
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