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Sun(Q),Wu(X),Li(X),Shi(F),Gao(Y),Ji(J),Gua... BMC Biol 2026-03-16

...RAC1 axis. LAMB1 promotes inflammation and coagulation dysfunction in SCH by regulating COL3A1 and RAC1 expression. Targ...

Li(K),Shen(C),Li(Y),Zhang(Q),Guo(J) Respir Res 2026-03-18

...RAC1 was identified as a downstream target via gene set enrichment analysis (GSEA) and correlation analysis. Glycolytic ...

Parapini(S),D'Alessandro(S),Travaglione(S)... Eur J Med Chem 2026-04-15

In this research, we validate that inhibitors of host-cell-Rac1 can provide a novel strategy for antimalarial therapy. H...

Kuraoka(S),Higashi(Y),Saito(S),Pourgonabad... Adv Sci (Weinh) 2026-05-00

...RAC1/c-FOS as potential therapeutic targets. However, critical questions remain regarding RAC1 activation during cyst fo...

Pineda(C),Cohen(E),Su(B),Yeom(J),Kim(J),Le... Mol Biol Cell 2026-05-01

...Rac1 and its activator Dock7. Biochemically, we confirmed that Rac1 and K17 interact directly in vitro and in A431 tumor...

Zeng(Y),Yang(D),Zhao(J),Yuan(P),Jin(H),Lia... J Struct Biol 2026-05-25

...Rac1P29S) caused by a mutation at a primary anchor residue. Unlike typical cases, the immunogenicity of Rac1P29S stems f...

Alharthy(FH),Alsughayyir(J),Alfhili(MA) Int J Mol Sci 2026-05-13

...Rac1 GTPase/NOS/COX pathway. Altogether, these findings present a novel mechanistic link between lipid dysregulation and...

Alfhili(MA),Alruwaili(SH),Alsughayyir(J) Molecules 2026-05-12

...Rac1 GTPase ameliorated eryptosis and hemolysis, the latter was only prevented by caspase, nitric oxide synthase, or ser...

Shen(H),Ni(Z),Guo(H),Liu(X),Zhao(Y),He(X),... Pharmaceuticals (Basel) 2026-05-02

...RAC1/PIP4K2 axis. Molecular docking results suggested its strong binding affinity and specificity. In vivo studies confi...

Zhu(J),Zhu(X),Lin(X),Zhou(Q),Chen(W),Liu(Y... J Ethnopharmacol 2026-10-28

...Rac1 activation assays. Oral administration of QZCEE significantly ameliorated the severity of DSS-induced colitis, evid...