Yamashita(T),Kodera(N),Eto(M),Omura(R),Hir... Proc Natl Acad Sci U S A 2026-07-28

...ROCK2 in the presence of calyculin A was indistinguishable between the trimer and dimer complexes, the subsequent autode...

Yin(X),Hao(Y),Ma(Z),Xie(Y),Bao(B),Wei(H),W... Front Biosci (Landmark Ed) 2026-01-16

...ROCK2, α-smooth muscle actin (α-SMA), and matrix metalloproteinase (MMP)1 were significantly elevated in the myopic cili...

Araki(T),Yashima(H),Kaneta(A),Takei(H),Kob... Am J Health Syst Pharm 2026-02-20

...ROCK2 inhibitor used in the treatment of chronic graft-vs-host disease. Given that pharmacological activity has been rep...

Lange(M),Francis(C),Furtado(J),Granger(J),... Cardiovasc Res 2026-02-14

...ROCK2 correlated with ROCK2 substrate specificity for FAK and LIMK. By analysing single and three allele mutants we show...

Panneerselvam(S),Sharma(N),Andugulapati(SB... Eur J Pharmacol 2026-01-20

...ROCK2/p-cofilin-1/pNFκB signaling pathway, whereas OBT treatment significantly modulated these molecular pathways. OBT a...

Gao(Q),Tang(W),Mi(Z),He(S),Yang(H),Wang(F)... Cancer Cell Int 2026-01-07

...ROCK2. In OC regulation, RND3 interacted with ROCK1 and ROCK2, exerted influence on Smad2/3 activation, which in turn co...

Leung(GMK),Sim(JPY),Chan(TSY),Cheung(CYM),... Ann Hematol 2026-02-04

...ROCK2 inhibitor belumosudil in moderate to severe cGVHD that had failed ≥ 2 lines of systemic therapies, in order to eva...

Jin(R),Zhou(Z),Lou(Y),Wang(X),Lv(B),Chen(Z... J Agric Food Chem 2026-01-28

...ROCK2/MLC pathway, downregulating occludin and claudin-1. Paeoniflorin targeted CRFR1, inhibited ROCK2 and MLC phosphory...

Gün(E),Sevgi(S),Demirçi(B),Arıca(İE),Helva... Eur J Clin Pharmacol 2026-01-19

...ROCK2 inhibitors, S1P1 modulators, and IRAK4/RIPK1 inhibitors. Among these, oral TYK2 inhibitors have shown the most con...

Chen(Q),Shen(Z),Wang(Q),Jiao(R),Liu(Y),Men... Mamm Genome 2026-01-12

...Rock2 as a direct target of miR-324-5p. Rock2 overexpression reversed the protective effects of miR-324-5p on apoptosis ...