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Inhibition of Pax6 sumoylation suppresses the tumorigenicity of pancreatic ca...

Xiao(Y),Wang(JM),Shan(YY),Fu(JL),Deng(M),W... Cell Death Differ 2026-06-25

...SUMO1 at the primary residue, Lys-91, and to a less degree at Lys-110 of the p32 Pax6 (K91/110) (Yan et al., 2010, PNAS)...

Low Zinc Ameliorated the Decrease in Intestinal Copper Level Induced by Low D...

Zhong(CC),Yang(H),Hogstrand(C),Song(CC),Zh... FASEB J 2026-06-15

...Sumo1-overexpression significantly reduced atp7a promoter activity. Taken together, dietary low Zn alleviated low Cu-ind...

TRIM47 catalyzes MAVS SUMOylation to safeguard chronic viral infections and t...

Lu(W),Xing(J),Wang(J),Minze(LJ),Li(XC),Zha... Cell Commun Signal 2026-07-15

...SUMO1-mediated MAVS SUMOylation at K297 and K348, thereby enhancing MAVS aggregation and activation and driving robust I...

Blocking the aryl hydrocarbon receptor (AhR) protects CD4+ T cells from Th17/...

Ge(J),Liu(Y) Hum Immunol 2026-07-17

...SUMO1, which enhanced AhR protein stability and transcriptional activity; this modification was reversed by SENP1-mediat...

KAP1 SUMOylates and stabilizes SR-A to facilitate glycated LDL transcytosis a...

Shu(M),Cheng(W),Yu(F),Zhang(L),Wang(L),Shu... Cell Mol Biol Lett 2026-05-30

...SUMO1 modification of the SR-A lysine (K)22, which hampers K48-linked ubiquitination and proteasomal degradation of SR-A...

Slice Collision-Induced Unfolding and Molecular Dynamics Reveal How Post-Tran...

Groignet(L),Robert(T),Duez(Q),Claessens(J)... J Am Soc Mass Spectrom 2026-08-05

...SUMO1 with modified properties. The present study assesses the structural and gas-phase stability modifications in SUMO1...

SUMOylation activates ECHS1 for adaptive catabolism in lung cancer.

Chen(Y),Mao(H),Cai(L),Li(Q),Song(J),Zhang(... Cell Death Dis 2026-07-09

...SUMO1 modification at lysine 128 of ECHS1 as an essential activation switch that drives mitochondrial catabolism and res...

Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-Ran...

Baytshtok(V),DiMattia(MA),Lima(CD) Nat Commun 2025-07-11

The human nucleoporin RanBP2/Nup358 interacts with SUMO1-modified RanGAP1 and the SUMO E2 Ubc9 at the nuclear pore compl...

SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylatio...

El Motiam(A),Bouzaher(YH),Chen(H),Seoane(R... Cell Death Dis 2025-07-12

...SUMO1, SUMO2, and UBC9, globally augmenting SUMOylation. Finally, p14ARF contributes to MLN4924-driven cytotoxicity of p...

Gene delivery of SUMO1-derived peptide rescues neuronal degeneration and moto...

Liang(Z),Murugappan(SK),Li(Y),Lai(MN),Qi(Y... Mol Ther 2025-07-02

...SUMO1-derived peptide, SUMO1(15-55), that exhibits tight binding to monomeric α-synuclein via SUMO-SUMO-interacting moti...

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