Literature Search

Mills(AM),Vidis(L),Carlson(DK),Crawford(MP),… Hum Pathol 2026-08-18

...TSC2 alterations which was reclassified from high-grade carcinoma to malignant PEComa. Adverse outcomes were seen in 0% ...

Aggarwal(A),Pappuru(RR),Sadda(S),Narayanan(R… BMJ Case Rep 2026-08-21

...TSC2 (tuberin) gene mutation, known to affect the mammalian target of rapamycin (mTOR) signalling pathway. To understand...

Zullow(H),Tjota(MY),Kwon(JW),Antic(T) Histopathology 2026-08-13

...TSC2 gene variants in ESC-RCC and TFEB gene locus amplification in TFEB-amplified RCC. Although ESC-RCC and TFEB-RCC sha...

van Altena(PFJ),Ransanz(LC),Guis(RH),Bergama… Adv Mater 2026-08-17

...TSC2 gene mutation linked to tuberous sclerosis complex (TSC). The proposed elastomeric microenvironment paves the way f...

Tao(J),Chen(S),Liu(N),Gong(Y),Zhang(S),He(J)… FASEB J 2026-08-31

...tsc2 knockdown rescued mTOR phosphorylation. Furthermore, mTOR inhibition by rapamycin abolished insulin-induced SREBP1 ...

Li(K),Du(H),Wang(Y),Khabibullin(D),Alchoueir… Oncogene 2026-09-00

...Tsc2 deletion at E17.5, which revealed a distinct tumor cell population characterized by intercalated cell signatures, c...

Gu(NH),Luo(LJ),Yang(NP),Yang(YP),Li(GJ),Ou-Y… Reprod Sci 2026-08-00

The TSC complex, formed by the binding of TSC2 with TSC1 and TBC1D7, plays an important role in the onset of endometrial...

Dogra(S),Zmorzynska(J) J Vis Exp 2026-06-26

...TSC2 mutations) exhibit variable expressivity of autism spectrum disorder (ASD), and maternal immune activation is known...

Chen(X),Gao(H),Wu(W),Shi(P),Chen(Y),Zhang(A)… Adv Sci (Weinh) 2026-08-27

...TSC2), mediating its degradation. TSC2 loss relieves mechanistic target of rapamycin complex 1 (mTORC1) inhibition, resu...

Salahat(D),Mujahed(R),Jaber(M),Tahayneh(M),K… Oxf Med Case Reports 2026-01-00

...TSC2 genes. Postnatal imaging revealed bilateral polycystic kidney disease by 2 months of age. The patient presented wit...