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Regulation of bone homeostasis by MERTK and TYRO3.

Engelmann(J),Zarrer(J),Gensch(V),Riecken(K),… Nat Commun 2022-00-12

...VAV2-RHOA-ROCK axis leading to increased cell contractility and motility while TYRO3 antagonizes this effect. Consequent...

Aberrant B-Cell Activation in Systemic Lupus Erythematosus.

Kang(N),Liu(X),You(X),Sun(W),Haneef(K),Sun(X… Kidney Dis (Basel) 2022-12-00

...VAV2, PLC-γ2), TLR pathway (TLR9, P105, IRF7, TAB1), and BAFF-R pathway (SDF-1α) are attitudinally upregulated in SLE pa...

VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulat…

Veluthakal(Rajakrishnan),Tunduguru(Ragadeept… Diabetologia 2016-07-26

...VAV2 (VAV2), a member of the Dbl family of proteins, has been identified as one of the GDP/GTP exchange factors for Rac1...

Regulation of sarcoma cell migration, invasion and invadopodia formation by AFA…

Tie(S R),McCarthy(D J),Kendrick(T S),Louw(A)… Oncogene 2016-09-15

...Vav2 and Nck2 SH2 domains, respectively. These phosphotyrosine motifs are essential for AFAP1L1-mediated cytoskeleton re...

Genome-wide whole blood microRNAome and transcriptome analyses reveal miRNA-mRN…

Bao(Hua),Kommadath(Arun),Liang(Guanxiang),Su… Sci Rep 2016-07-28

...VAV2. We showed that challenged pigs had reduced miR-214 expression and increased miR-331-3p expression in the whole blo...

Structural basis for a novel interaction between TXNIP and Vav2.

Liu(Shasha),Wu(Xue),Zong(Minru),Tempel(Wolfr… FEBS Lett 2016-08-08

...Vav2 and Src with dissociation constants around 10 μm and that phosphorylation is indispensable for these interactions a...

Receptor tyrosine kinase c-Met controls the cytoskeleton from different endosom…

Ménard(Ludovic),Parker(Peter J),Kermorgant(S… Nat Commun 2015-07-15

...Vav2 are required. Thus we describe a novel endosomal signalling mechanism whereby one signal output, Rac1, is stimulate...

Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia…

Wan(Ya-Juan),Yang(Yin),Leng(Qian-Li),Lan(Bei… Cell Signal 2015-09-02

...Vav2 and Vav3 are ubiquitously distributed in almost all human tissues. All three Vav proteins contain conserved structu...

cAMP with other signaling cues converges on Rac1 to stabilize the endothelial b…

Schlegel(Nicolas),Waschke(Jens) Cell Tissue Res 2015-01-21

...Vav2 and stabilize the endothelial barrier via Rac1-mediated enforcement of adherens junctions and strengthening of the ...

Vav2 protein overexpression marks and may predict the aggressive subtype of duc…

Jiang(YunQing),Prabakaran(Indira),Wan(Fei),M… Biomark Res 2015-03-18

...Vav2 were more than twice as likely to progress to invasive cancers as DCIS with low Vav2 (odds ratio, 2.42; 95% CI, 1.2...

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