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The human Y and inactive X chromosomes similarly modulate autosomal gene expres…

San Roman(AK),Skaletsky(H),Godfrey(AK),Bokil… Cell Genom 2024-01-10

...ZFX and ZFY-encoded by Chr X and Y. This demonstrates sex-shared mechanisms by which Xi and Y modulate autosomal express...

Reduction of ZFX levels decreases histone H4 acetylation and increases Pol2 pau…

Hsu(E),Hutchison(K),Liu(Y),Nicolet(CM),Schre… Nucleic Acids Res 2024-07-08

...ZFX increased Pol2 pausing at ZFX-regulated promoters. To further investigate the mechanisms by which ZFX regulates tran...

Maintenance of stem cell self-renewal by sex chromosomal zinc-finger transcript…

Kita(K),Morkos(C),Nolan(K) World J Methodol 2024-12-20

...ZFX). ZFX and ZFY are both zinc-finger proteins that encode general transcription factors abundant in hematopoietic and ...

Comparing the roles of sex chromosome-encoded protein homologs in gene regulati…

Lavorando(E),Owens(MC),Liu(KF) Genes Dev 2024-08-20

...ZFX/ZFY, KDM5C/KDM5D, UTX/UTY, and TBL1X/TBL1Y. Their mechanisms of gene regulation are discussed, including any redunda...

A Germline ZFX Missense Variant in a Patient With Primary Hyperparathyroidism.

Guan(B),Agarwal(SK),Welch(JM),Jha(S),Weinste… JCEM Case Rep 2024-08-00

...ZFX gene that encodes a zinc-finger transcription factor previously shown to harbor somatic missense variants in a subse...

Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal an…

Blanton(LV),San Roman(AK),Wood(G),Buscetta(A… Cell Genom 2024-09-11

...ZFX and ZFY accounted for a significant fraction of these autosomal responses both in vivo and in vitro. We conclude tha...

Single-nucleus multiomics reveals the gene-regulatory networks underlying sex d…

Alexander(AK),Rodriguez(KF),Chen(YY),Amato(C… bioRxiv 2024-09-25

...ZFX. Sex-specific enrichment of the forkhead-box and POU6 families of transcription factors was also observed in XY PGCs...

Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal an…

Blanton(LV),San Roman(AK),Wood(G),Buscetta(A… bioRxiv 2024-03-19

...ZFX and ZFY accounted for a significant fraction of these autosomal responses both in vivo and in vitro . We conclude th...

The human Y and inactive X chromosomes similarly modulate autosomal gene expres…

San Roman(AK),Skaletsky(H),Godfrey(AK),Bokil… bioRxiv 2023-06-07

...ZFX and ZFY - encoded by Chr X and Y. This demonstrates sex-shared mechanisms by which Xi and Y modulate autosomal expre...

Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the …

Lin(Z),Lin(J) Cell Mol Bioeng 2023-04-00

...ZFX was verified by a dual-luciferase reporter assay. Circ_0004585 and ZFX were up-regulated, while miR-338-3p was down-...

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