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Transcriptional mechanisms of sex-biased gene expression and their connections …

Jones(AG),Dalapati(T),Connelly(GG),Wang(L),S… Hum Mol Genet 2026-03-23

...ZFX, and ZNF726 appear to make the largest contribution to this based on machine learning and linear modeling approaches...

The Y Chromosome is a Reliable Marker for Deep-Time Phylogenetic Inference.

Alexander(EP),Foley(NM),Murphy(WJ) Syst Biol 2026-07-22

...ZFX and ZFY genes has independently occurred in multiple lineages. ZFY has a proposed function as a meiotic executioner,...

Systematic identification of single transcription factor perturbations that dri…

Sengstack(J),Zheng(J),Aghayev(T),Bieri(G),Mo… Proc Natl Acad Sci U S A 2026-01-13

...ZFX, reversed cellular hallmarks of aging-increasing proliferation, proteostasis, and mitochondrial activity, while decr...

Species delimitation based on phylogenetic analyses of males: A case study reve…

Hassanin(A),Jullemier(E),Chardonnet(B),Robin… Mol Phylogenet Evol 2026-05-00

...ZFX alleles showing evidence of ancient introgression between the two taxa. The delimitation of Giraffa in two species i...

Integrative Bioinformatics Analyses Reveal X Chromosome Inactivation Escape Gen…

Liang(H),Li(Z),Zhang(F) Iran J Biotechnol 2026-04-00

...ZFX), which may serve as core pathogenic factors in Turner Syndrome. Additionally, based on our findings, we proposed ce...

De Novo Heterozygous ZFX Frameshift Variant in a Female With an X-Linked Neurod…

Showpnil(IA),Daley(A),Sites(ER),Plourde(SM),… Am J Med Genet A 2026-02-00

Germline ZFX variants are associated with an X-linked neurodevelopmental disorder, with 14 males and 16 females reported...

Tightening the Sphincter on Faecal Sample Anonymity: The Case of the Weddell Se…

van den Hoff(J),Fanson(KV),Polanowski(A),Wot… Zoo Biol 2026-06-06

...ZFX/ZFY loci successfully sex-typed 96% of the samples collected. Of the range of predictive models tested, the generali...

Single-cell multiomics gene regulatory landscape reveals impaired spermatogonia…

Lin(N),Zhang(Z),Sha(X),Yao(J),Sun(X),Sun(R),… J Genet Genomics 2026-05-20

...ZFX as a consistently downregulated transcription factor in early germ cells, linking its decline to compromised SSC mai...

Interpretable deep learning framework for understanding molecular changes in hu…

Trivedi(MR),Joshi(AM),Shah(J),Readhead(BP),W… NPJ Aging 2025-07-16

...ZFX/ZFY) associated with more pronounced neuronal loss in AD females, shedding light on a novel mechanism for sex dimorp...

Expansion of the phenotype in ZFX neurodevelopmental disorder in a family.

van der Tol(L),de Jong(M),Alders(M),Wilke(M)… Eur J Med Genet 2025-12-00

...ZFX variant. In this report, we present a male patient and his mother with a new likely pathogenic variant in the ZFX ge...

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