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An activating mutation in the PDGF receptor-beta causes abnormal morphology i...

Looman(Camilla),Sun(Tong),Yu(Yang),Zieba(A... Int J Dev Biol 2007-10-05

...Pdgfrb), the corresponding aspartic acid residue at position 849 of Pdgfrb was changed into valine (D849V) using a knock...

Common deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythr...

Lehmann(S),O'Kelly(J),Raynaud(S),Funk(S E)... Leukemia 2007-10-11

...PDGFRB; 73%), Nef-associated factor 1 (TNIP1; 72%), secreted protein, acidic and rich in cysteine (SPARC; 71%), annexin ...

Platelet-derived growth factor receptor-beta constitutive activity promotes a...

Magnusson(Peetra U),Looman(Camilla),Ahgren... Arterioscler Thromb Vasc Bi... 2007-10-11

...Pdgfrb(D849V)) introduced into embryonic stem cells with respect to vasculogenesis/angiogenesis in vitro and in vivo.,Em...

Cyclooxygenase-2 and platelet-derived growth factor receptors as potential ta...

Signoroni(Stefano),Frattini(Milo),Negri(Ti... Clin Cancer Res 2007-09-25

...PDGFRB, which in turn paralleled the presence of their cognate ligands. No PDGFRB mutations were found. The results are ...

Insertional mutagenesis by replication-deficient retroviral vectors encoding ...

Li(Zhixiong),Kustikova(Olga S),Kamino(Kenj... Ann N Y Acad Sci 2007-08-30

...Pdgfrb, Osm/Lif, Axl, Fli, Sema4b, Sox4). 32D-derived monocytic leukemias showed hits in Pim2 and Max proto-oncogenes, o...

Characterization of three new imatinib-responsive fusion genes in chronic mye...

Walz(Christoph),Metzgeroth(Georgia),Haferl... Haematologica 2007-03-26

...PDGFRB exon 11. In case #3, LDI-PCR revealed a fusion between PRKG2 exon 5 and a truncated PDGFRB exon 12. The region en...

Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarc...

Do(Ingu),Araujo(Eduard Santini),Kalil(Rica... Pathol Res Pract 2007-05-04

...PDGFRB gene in 71 formalin-fixed, paraffin-embedded Ewing sarcomas to increase our understanding of the potential, if an...

The identification of (ETV6)/RUNX1-regulated genes in lymphopoiesis using his...

Starkova(Julia),Madzo(Jozef),Cario(Gunnar)... Clin Cancer Res 2007-06-13

...PDGFRB, and TCF4), we confirmed expression changes after HDACi by quantitative analysis. After HDACi treatment, ETV6/RUN...

Tyrosine kinases as therapeutic targets in BCR-ABL negative chronic myeloprol...

Reiter(Andreas),Walz(Christoph),Cross(Nich... Curr Drug Targets 2007-05-31

...PDGFRB, FGFR1 or c-KIT and the non-receptor tyrosine kinases JAK2 and ABL. Activation occurs as a consequence of specifi...

Differential expression of hypoxia and (lymph)angiogenesis-related genes at d...

Van den Eynden(Gert G),Van Laere(Steven J)... Clin Exp Metastasis 2007-06-01

...PDGFRB, FGF4, TIMP1, TGFB-R1 and collagen 18A1 (precursor of endostatin). To confirm the results of these experiments at...

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