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Interruption of macrophage-derived IL-27(p28) production by IL-10 during seps...

Bosmann(Markus),Russkamp(Norman F),Strobl(... J Immunol 2015-04-16

...SOCS3 in Tie2-Cre/SOCS3flox macrophages. Blockade of IL-10R by Ab or genetic deficiency of IL-10 resulted in 3-5-fold hi...

Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α si...

Jiang(Youde),Biswas(Subrata K),Steinle(Jen... Mol Vis 2015-06-26

...SOCS3 to induce increased levels of these proteins.,In cells with IRS-1(Ser307Ala), TNF-α and SOCS3 failed to phosphoryl...

Japanese encephalitis virus upregulates the expression of SOCS3 in mouse brai...

Li(Xiangmin),Zhu(Qiaoyan),Cao(Qishu),Chen(... Viruses 2015-10-19

...SOCS3 expression, upregulating both the mRNA and protein levels in Raw264.7 cells in a time-dependent manner. The SOCS3 ...

Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-i...

Thagia(Imtiyaz),Shaw(Elisabeth J),Smith(Em... Am J Physiol Gastrointest L... 2015-03-04

...SOCS3 enhances TLR5-induced TNF-α. We also show that flagellin promotes transcription of TNFR2 and that SOCS3 limits thi...

Platelet factor 4 inhibits IL-17/Stat3 pathway via upregulation of SOCS3 expr...

Fang(Shanshan),Liu(Bo),Sun(Qiushi),Zhao(Ju... Inflammation 2015-06-22

...SOCS3) upregulations, and PF4 fails to suppress expression of p-Stat3, IL-17, and IL-6 in cells transfected with SOCS3 s...

Intravitreal injection of IGFBP-3 restores normal insulin signaling in diabet...

Jiang(Youde),Zhang(Qiuhua),Steinle(Jena J) PLoS One 2015-01-29

...SOCS3), and insulin receptor signaling partners using Western blotting or ELISA. Data show that a single intraocular inj...

Cyclic AMP and the regeneration of retinal ganglion cell axons.

Hellström(Mats),Harvey(Alan R) Int J Biochem Cell Biol 2015-08-17

...SOCS3) activity in RGCs. Another target for cAMP is the exchange protein activated by cAMP (Epac), which can also mediat...

Cannabinoid receptor 1 disturbance of PPARγ2 augments hyperglycemia induction...

Lin(Chun-Liang),Hsu(Yung-Chien),Lee(Pei-Hs... J Mol Med (Berl) 2015-01-27

...SOCS3, proinflammatory cytokines, and accumulation of fibrotic matrix. PPARγ agonist rosiglitazone reduced the hyperglyc...

[Effects of exogenous suppressor of cytokine signaling on cell apoptosis in e...

Li(Min),Ruan(Fei),Zhan(Hong),Fei(Xiangwei)... Zhonghua Yi Xue Za Zhi 2015-02-09

...SOCS3 and GFP (green fluorescent protein) recombinant (LV-SOCS3-GFP) or only GFP gene (LV-GFP) was used to transfect two...

Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association w...

Wang(Z F),Li(Q),Liu(S B),Mi(W-L),Hu(S),Zha... Neuroscience 2015-02-09

...SOCS3) mRNA in the spinal cord induced by CCI surgery. Taken together, our results suggested that the analgesic effect o...

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