Literature Search

Ferguson(Gregory D),Delgado(Mercedes),Plante… PLoS One 2016-07-19

...Syk kinase inhibitor, CC-509. This compound is a potent inhibitor of purified Syk enzyme, FcR-dependent and FcR-independ...

Wu(Nan-Lin),Huang(Duen-Yi),Wang(Li-Fang),Kan… J Invest Dermatol 2016-05-20

...Syk are under development for inflammatory diseases. Syk expression in the skin has been detected, but its functions in ...

Ma(Frank Y),Blease(Kate),Nikolic-Paterson(Da… Life Sci 2016-06-13

...Syk can also be expressed by some non-haematopoietic cell types, although whether Syk signalling in these cells contribu...

Shirley(Devon),McHale(Cody),Gomez(Gregorio) Biochim Biophys Acta 2016-05-05

...Syk, Akt, p38, and p42/44 (ERKs) remained intact. Surprisingly, TNF production was significantly enhanced with Resveratr...

Heizmann(Beate),Sellars(MacLean),Macias-Garc… Biochem Biophys Res Commun 2016-06-13

...SYK, BTK, AKT and LYN. Stimulation results in enhanced and prolonged ERK and p38 phosphorylation, followed by hyper-prol...

Kim(So-Young),Park(Sang Eun),Shim(Sang-Mi),P… PLoS One 2016-06-28

...Syk) inhibitor Bay 61-3606 was identified as a TRAIL sensitizer. Amplification of TRAIL-induced apoptosis by Bay 61-3606...

Iwata(Shigeru),Tanaka(Yoshiya) Nihon Rinsho Meneki Gakkai Ka… 2016-09-01

...Syk/Btk/JAK caused robust gene expression of AICDA, BCL6, XBP1 and IgG production. We found that levels of Syk/Btk phosp...

Draberova(Lubica),Paulenda(Tomas),Halova(Iva… PLoS One 2016-06-27

...SYK kinases, LAT adaptor protein, phospholipase Cγ, STAT5, and AKT and internalization of aggregated FcεRI. Interestingl...

Llop-Guevara(Alba),Porras(Mónica),Cendón(Car… Arthritis Res Ther 2016-08-12

...SYK kinase, since both kinases mediate complementary and non-redundant pathways in RA.,Efficacy of dual JAK + SYK inhibi...

Park(Ga Bin),Kim(Yeong Seok),Lee(Hyun-Kyung)… Mol Cell Biochem 2016-10-31

...Syk/Src-mediated PI3K/Akt activation, in baicalein-treated EBV-transformed B cells. Meanwhile, ASK1/JNK-dependent TAp63 ...