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Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction …

Kotla(Sivareddy),Rao(Gadiparthi N) J Biol Chem 2016-04-21

...Syk and Pyk2 stimulation is required for p300 tyrosine phosphorylation and activation. Together, these results demonstra...

Targeting Syk in Autoimmune Rheumatic Diseases.

Deng(Guo-Min),Kyttaris(Vasileios C),Tsokos(G… Front Immunol 2016-03-25

Spleen tyrosine kinase (Syk) is a member of the Src family of non-receptor tyrosine kinases, which associates directly w...

Interventions for the management of fatigue in adults with a primary brain tumo…

Day(Julia),Yust-Katz(Shlomit),Cachia(David),… Cochrane Database Syst Rev 2016-07-21

...SYK, DC) independently evaluated search results, extracted data from selected studies and carried out a bias risk assess...

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses …

Németh(Tamás),Futosi(Krisztina),Sitaru(Cassi… Nat Commun 2016-08-19

...Syk, PLCγ2, Bcl10/Malt1 and NFκB. Collectively, CARD9-mediated gene expression changes within neutrophils play important...

Membrane immunoglobulin expressed by retroviral vector gene transfer mimics par…

Lu(Jing),Chen(Feng),Xu(Zhen),Zhang(Lingling)… Sci China Life Sci 2016-10-31

...Syk and Erk1/2 proteins. The results showed that B-cells expressing membrane immunoglobulin can make proliferative respo...

The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammator…

Zhao(Dianyuan),Han(Xintao),Zheng(Xuexing),Wa… PLoS Pathog 2016-08-26

...Syk activation. Mutation of key tyrosines in the DAP12 immunoreceptor tyrosine-based activation motif abrogated LSECtin-...

Structural and Biochemical Characterization of the Early and Late Enzymes in th…

Pereira(Jose Henrique),Heins(Richard A),Gall… J Biol Chem 2016-11-08

...SYK-6 bacteria. β-Aryl ether units are typically abundant in lignin, corresponding to 50-70% of all of the intermonomer ...

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Developme…

Lee(Ellen J),Brown(Brieanna R),Vance(Emily E… J Immunol 2016-08-03

...Syk and Card9. In contrast, Dectin-1 contributed minimally and a possible repressive role was shown for Dectin-2. These ...

Effects of Cymbidium Root Ethanol Extract on Atopic Dermatitis.

Kim(Wan-Joong),Cha(Hae-Sim),Lee(Myung-Hun),K… Evid Based Complement Alterna… 2016-03-16

...Syk), an upstream molecule. It also inhibited the phosphorylation of Akt, phospholipase C- (PLC-) γ, and mitogen-activat...

The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signali…

Yaron(Jordan R),Rao(Mounica Y),Gangaraju(San… Biochem Biophys Res Commun 2016-08-08

...Syk phosphorylation. The effects of OXSI-2 identified in this study provide context for the role of Syk in inflammasome ...

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