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Spleen Tyrosine Kinase Mediates EGFR Signaling to Regulate Keratinocyte Termina…

Wu(Nan-Lin),Huang(Duen-Yi),Wang(Li-Fang),Kan… J Invest Dermatol 2016-05-20

...Syk are under development for inflammatory diseases. Syk expression in the skin has been detected, but its functions in ...

The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signali…

Yaron(Jordan R),Rao(Mounica Y),Gangaraju(San… Biochem Biophys Res Commun 2016-08-08

...Syk phosphorylation. The effects of OXSI-2 identified in this study provide context for the role of Syk in inflammasome ...

TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macro…

Lin(Jia),Kurilova(Svetlana),Scott(Brandon L)… BMC Immunol 2016-09-30

...Syk with nascent clusters of antibodies indicated that phosphorylated receptor complexes underwent maturation as they tr...

Pancreas-protective effect of rituximab for acute-onset type 1 diabetes in the …

Kurozumi(Akira),Okada(Yosuke),Arao(Tadashi),… Endocrinol Diabetes Metab Cas… 2016-06-02

...Syk levels in AOT1DM patients remains unclear, the difference in the change in Syk level between the two patients may ex...

Inhibition of Sophocarpine on Poly I: C/D-GalN-Induced Immunological Liver Inju…

Huang(Yin-Qiu),Li(Peng-Yan),Wang(Jia-Bo),Zho… Front Pharmacol 2016-08-29

...Syk decreased, as did their corresponding mRNA levels. Overall, our study demonstrates that Sophocarpine inhibits NK cel...

Computational Search for Possible Mechanisms of 4-Thiazolidinones Anticancer Ac…

Devinyak(Oleg),Havrylyuk(Dmytro),Zimenkovsky… Mol Inform 2016-08-04

...SYK. Several compounds from this group show strong negative correlation with fraction of methylated CpG sites in HOXA5. ...

Reversion of Asthmatic Complications and Mast Cell Signalling Pathways in BALB/…

Gupta(Kriti),Kumar(Sandeep),Gupta(Rinkesh Ku… J Biomed Nanotechnol 2016-07-12

...Syk, c-Yes, PI-3, p-PI-3, PLC-γ2, and p-PLC-γ2 were found to be reduced in the OVA sensitized BALB/c mice treated with n...

Targeting B-cell receptor signaling kinases in chronic lymphocytic leukemia: th…

Sharman(Jeff),Di Paolo(Julie) Ther Adv Hematol 2016-06-01

...SYK), Bruton's tyrosine kinase, and phosphoinositide 3-kinase delta. This review discusses the rationale for targeting t...

Inhibitory Effects of Angelica Polysaccharide on Activation of Mast Cells.

Mao(Wei-An),Sun(Yuan-Yuan),Mao(Jing-Yi),Wang… Evid Based Complement Alterna… 2016-05-20

...Syk pathways.

Expression of SOCS1 and CXCL12 Proteins in Primary Breast Cancer Are Associated…

Smolkova(Bozena),Mego(Michal),Horvathova Kaj… Transl Oncol 2016-06-09

...SYK, TIMP3, BRMS1, and SOCS1 proteins in primary breast tumor tissue was evaluated by immunohistochemistry. CTCs with ep...

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