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IL-10-overexpressing B cells regulate innate and adaptive immune responses.

Stanic(Barbara),van de Veen(Willem),Wirz(O... J Allergy Clin Immunol 2015-04-30

...SOCS3), glycoprotein A repetitions predominant (GARP), the IL-2 receptor α chain (CD25), and programmed cell death 1 lig...

Psoriatic inflammation facilitates the onset of arthritis in a mouse model.

Yamamoto(Mayuko),Nakajima(Kimiko),Takaishi... J Invest Dermatol 2015-03-24

...SOCS3-dependent negative regulation. Here, we crossed F759 mice with K5.Stat3C transgenic mice, in which keratinocytes e...

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident c...

Steffensen(Maria Abildgaard),Fenger(Christ... J Virol 2015-01-21

...SOCS3 expression in the context of virus-induced CNS infection. We found that both a noncytolytic and a cytolytic virus ...

Depletion of white adipose tissue in cancer cachexia syndrome is associated w...

Tsoli(Maria),Schweiger(Martina),Vanniasing... PLoS One 2015-01-30

...SOCS3 gene expression levels. In addition perturbations in circadian regulation of lipid metabolism were also observed. ...

Japanese encephalitis virus upregulates the expression of SOCS3 in mouse brai...

Li(Xiangmin),Zhu(Qiaoyan),Cao(Qishu),Chen(... Viruses 2015-10-19

...SOCS3 expression, upregulating both the mRNA and protein levels in Raw264.7 cells in a time-dependent manner. The SOCS3 ...

Loss of suppressors of cytokine signaling 3 promotes aggressiveness in hepato...

Wu(Wen-Yong),Kim(Hyunchul),Zhang(Chang-Le)... J Invest Surg 2015-03-30

...SOCS3 in the tumorigenesis and progression of HCC is not fully understood. In this study we intended to show that SOCS3 ...

LIF/STAT3/SOCS3 signaling pathway in murine bone marrow stromal cells suppres...

Matsushita(Kenta),Itoh(Shousaku),Ikeda(Shu... J Cell Biochem 2015-01-10

...SOCS3). SOCS3 knockdown experiments have previously demonstrated that short-hairpin SOCS3-BMSCs reversed the LIF suppres...

Characterisation of the cytokine milieu associated with the up-regulation of ...

Martinez(Danica),Palmer(Clovis),Simar(Davi... Liver Int 2015-10-02

...SOCS3 expression. Immunological assays were employed to examine cytokine production.,There was increased expression of S...

Lactobacillus casei MYL01 modulates the proinflammatory state induced by etha...

Chiu(Yi-Heng),Tsai(Jaw-Ji),Lin(Shiao-Lin),... J Dairy Sci 2015-11-02

...SOCS3 expression via activation of TLR1, TLR2, TLR6, and TLR9, an action that cross-regulated ethanol-TLR4-nuclear facto...

Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-i...

Thagia(Imtiyaz),Shaw(Elisabeth J),Smith(Em... Am J Physiol Gastrointest L... 2015-03-04

...SOCS3 enhances TLR5-induced TNF-α. We also show that flagellin promotes transcription of TNFR2 and that SOCS3 limits thi...

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