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p53-Binding protein 1 is fused to the platelet-derived growth factor receptor...

Grand(Francis H),Burgstaller(Sonja),Kühr(T... Cancer Res 2004-12-03

We describe the fusion of TP53BP1 to PDGFRB in a patient with a chronic myeloid leukemia-like disorder associated with e...

Complete remission of TEL-PDGFRB-induced myeloproliferative disease in mice b...

Cain(Jennifer A),Grisolano(Jay L),Laird(A ... Blood 2004-08-17

The TEL-PDGFRB fusion oncogene is associated with chronic myelomonocytic leukemia (CMML) and results in the expression o...

Imatinib mesylate in chordoma.

Casali(Paolo G),Messina(Antonella),Stacchi... Cancer 2004-11-16

...PDGFRB, and in four patients PDGFRB was shown to be phosphorylated/expressed.,After a treatment period of > or = 1 year,...

Novel translocations that disrupt the platelet-derived growth factor receptor...

Baxter(E Joanna),Kulkarni(Shashikant),Vizm... Br J Haematol 2003-03-21

...PDGFRB) gene at chromosome band 5q33 have been described in some patients, the most common being the t(5;12)(q33;p13). A...

Increased binding and chemotactic capacities of PDGF-BB on fibroblasts in rad...

Tada(Hiroya),Ogushi(Fumitaka),Tani(Kenji),... Radiat Res 2003-07-02

...PDGFRB. Scatchard analysis of the saturation data demonstrated an approximately twofold increase both in the number of P...

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ET...

Grisolano(Jay L),O'Neal(Julie),Cain(Jennif... Proc Natl Acad Sci U S A 2003-10-03

...PDGFRB and AE into lethally irradiated syngeneic mice. These mice (19/19, 100%) developed AML resembling M2-AML that was...

Response to imatinib mesylate in patients with chronic myeloproliferative dis...

Apperley(Jane F),Gardembas(Martine),Melo(J... N Engl J Med 2002-09-05

...PDGFRB fusion gene. The fourth patient had leukocytosis, eosinophilia, and a t(5;12) translocation involving PDGFRB and ...

Tyrosine kinase fusion genes in chronic myeloproliferative diseases.

Cross(N C P),Reiter(A) Leukemia 2002-07-19

...PDGFRB or FGFR1. These translocations result in the production of constitutively active tyrosine kinase fusion proteins ...

An overview of translocation-related oncogenesis in the chronic myeloid leuka...

Bain(Barbara J) Acta Haematol 2002-06-11

...PDGFRB and FGFR1. This contrasts with the frequent involvement of genes encoding transcription factors or other nuclear ...

Myeloproliferative disorders with translocations of chromosome 5q31-35: role ...

Steer(E Joanna),Cross(Nicholas C P) Acta Haematol 2002-06-11

...PDGFRB), a receptor tyrosine kinase that maps to 5q33. PDGFRB is disrupted by other translocations and to date four addi...

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