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Microglia in Alzheimer's Disease: From Homeostatic Guardians to Multifaceted Dr…

Ma(L),Zhao(Y),Cai(C),Liu(Q),Hu(X),Wang(L) Cells 2026-07-18

...SYK phagocytosis, Piezo1 mechanotransduction, TAM (Tyro3, Axl, Mer) receptor signaling, and metabolic regulators (HK2, i...

Targeting DNGR-1 with Fangchinoline Elevates Dendritic Cell Antigen Cross-Prese…

Liao(Y),Ren(Z),Zhou(J),Luo(H),Li(Y),Chen(D),… Adv Sci (Weinh) 2026-06-11

...Syk-Nox2 pathway, increasing phagosomal reactive oxygen species and membrane permeabilization to enable cytosolic antige...

Basal phosphorylation of SHIP1 by Lyn suppresses proinflammatory signaling in t…

Senevirathne(SE),Kanagy(WK),Hemmila(CR),Gree… J Immunol 2026-03-17

...Syk, drives second-messenger generation, and induces downstream Erk and Akt signaling and proinflammatory responses in m...

Evolution of TP53 abnormalities during CLL disease course is associated with te…

Olbertova(H),Plevova(K),Pavlova(S),Malcikova… BMC Cancer 2022-02-03

...SYK, and p-NFκB (P = 0.04, P = 0.01, and P = 0.02, respectively). Our study revealed that changes of telomere length ref...

Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lym…

Devin(J),Cañeque(T),Lin(YL),Mondoulet(L),Vey… Cancer Res 2022-00-15

...Syk inhibitors. Altogether, these data demonstrate that a subgroup of high-risk patients with DLBCL can be identified wi...

Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cel…

Wang(HN),Xiang(QA),Lin(HH),Chen(JN),Guo(WJ),… Molecules 2022-02-27

...SYK, NF-κB p65, ERK1/2, p38, and JNK. Moreover, 4-MU attenuated the PCA allergic reaction (i.e., less ear thickening and...

ML355 Modulates Platelet Activation and Prevents ABT-737 Induced Apoptosis in P…

Shpakova(V),Rukoyatkina(N),Al Arawe(N),Prile… J Pharmacol Exp Ther 2022-00-00

...Syk), or phospholipase Cγ2 phosphorylation in activated platelets. The main inhibitory effect of low doses of ML355 (1-2...

Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodie…

Wu(J),Nie(Y),Ma(Y),Hao(L),Liu(Z),Li(Y) Fish Shellfish Immunol 2022-04-00

...Syk, MARCKS) related to FcγR-mediated phagocytic signaling pathway in phagocytic mIgM+ lymphocytes were up-regulated sig...

Small but mighty: the human mycobiome as an immunopharmacological regulator of …

Ahmad(S),Usman(M),Bibi(M),Aftab(MN),Aslam(MS) Int Immunopharmacol 2026-09-15

...Syk-CARD9, NF-κB and inflammasome signaling. These pathways shape both pro-inflammatory Th17/IL-22 responses that reinfo...

GPX1-associated prognostic signature predicts poor survival in patients with ac…

Zhang(J),Peng(Y),He(Y),Xiao(Y),Wang(Q),Zhao(… Biochim Biophys Acta Mol Basi… 2022-00-01

...SYK and PAK1, which promote AML progression and the resistance to therapy. Furthermore, Additionally, GPX1-associated pr...

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