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Ursodeoxycholic acid attenuates sepsis-associated platelet dysfunction through …

Li(L),Yang(Q),Zhang(H),Qi(Y),Xie(Y),Ding(Z),… Int Immunopharmacol 2026-09-15

...Syk-PI3K-Akt phosphorylation, accompanied by platelet hyperactivation. UDCA was associated with increased TREM2 expressi...

Aqueous extract of Orostachys japonicus A. Berger exerts immunostimulatory acti…

Park(HJ),Yang(HJ),Kim(KH),Kim(SH) J Ethnopharmacol 2015-07-21

...Syk kinase was increased in OJ aqueous extract-treated group as compared to control. Phosphorylation of PLC-γ was increa...

Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires I…

Zhi(H),Dai(J),Liu(J),Zhu(J),Newman(DK),Gao(C… PLoS One 2015-00-00

...Syk were found to play key roles in IgG-induced platelet activation events. Taken together, our data suggest a complex f...

Investigation of genomic and transcriptomic risk factors in clopidogrel respons…

Yang(G),Alarcon(C),Chanfreau(C),Lee(NH),Frie… medRxiv 2023-12-07

...SYK and AKT1, suggesting an inhibitory role of LAIR1 in the Glycoprotein VI pathway. Notably, the CYP2C19 variants showe...

Fostamatinib effectiveness and safety for immune thrombocytopenia in clinical p…

González-López(TJ),Bermejo-Vega(N),Cardesa-C… Blood 2024-00-08

...Syk inhibitor used in adult primary immune thrombocytopenia (ITP), has been shown to be safe and effective in this disor...

Integrated analysis of gene expression and methylation profiles of 48 candidate…

Li(Zibo),Heng(Jianfu),Yan(Jinhua),Guo(Xinwu)… Breast Cancer Res Treat 0000-00-00

...SYK, TGFBR2, TNFRSF10D, WIF1, and WRN) annotated with potential TFBSs in the promoter regions showed negative correlatio...

The Role of Intramolecular Reactions and Chemical Degradation in the Apparent B…

Calle(B),Barlaam(B),Diène(C),Lenz(E),Martin(… Drug Metab Dispos 2024-06-17

In vitro metabolism studies of the spleen tyrosine kinase inhibitors AZ-A and AZ-B identified four unusual metabolites. ...

Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparativ…

Mokada-Gopal(L),Boeser(A),Lehmann(CHK),Drepp… J Immunol 2017-05-01

...Syk and Fc receptor-like 1 were downregulated. This dataset provides a framework for further functional analysis of newl...

SAP130 released by ferroptosis tubular epithelial cells promotes macrophage pol…

Zhang(J),Jiang(J),Wang(B),Wang(Y),Qian(Y),Su… Int Immunopharmacol 2024-03-10

...syk/NF-κB signaling, and M1 macrophages, in turn, aggravated TEC ferroptosis.

FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and …

Kroll(KW),Hueber(B),Balachandran(H),Afifi(A)… Mucosal Immunol 2024-08-00

...Syk), zeta chain-associated protein kinase 70 (ZAP70), and signaling lymphocytic activation molecule family 1 (SLAMF1), ...

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