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Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated h…

Berger(M),Raslan(Z),Aburima(A),Magwenzi(S),W… Haematologica 2020-00-00

...Syk and protein kinase C. The effects of oxLDL on platelet function and cAMP signaling were blocked by pharmacological i...

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic act…

Oh(EB),Kong(YJ),Kim(T),Jang(J),Yu(H),Park(JW… Sci Rep 2025-10-16

...Syk), linker for the activation of T cells (LAT), vav guanine nucleotide exchange factor 1 (Vav1), and Bruton tyrosine k...

P-Rex1 controls phagocytosis and the killing of bacteria by murine neutrophils …

Islam(P),Chu(JY),Chetwynd(SA),Walker(R),Hawk… Front Immunol 2025-00-00

...Syk. Recently identified adaptor functions of P-Rex1 in GPCR trafficking and glucose uptake do not seem to underlie its ...

Dexamethasone induced Dectin-1 activation enhances NLRP3 inflammasome activatio…

Koerber(RM),Oberbeck(S),Kotthoff(P),Daecke(S… Front Immunol 2025-00-00

...Syk-inhibitors led to diminished inflammasome activation as well as to less pyroptosis and apoptosis in response to β -g...

Myo1f, an Unconventional Long-Tailed Myosin, Is a New Partner for the Adaptor 3…

Navinés-Ferrer(A),Ainsua-Enrich(E),Serrano-C… Front Immunol 2019-00-00

...Syk phosphorylation, as well as SCF-dependent cell survival. This study examines its role in SCF-dependent migration and...

Reticulated platelets in coronary artery disease: a multidimensional approach u…

Kirmes(K),Han(J),Klug(M),Bloxham(CJ),Babyak(… Eur Heart J 2025-12-01

...SYK, and elevated reactive oxygen species production. RPs showed increased aggregation, spreading and greater recruitmen...

Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits plate…

Nayak(MK),Dhanesha(N),Doddapattar(P),Rodrigu… Blood Adv 2018-00-14

...Syk and PLCγ2 in response to collagen or convulxin in human and mouse platelets (P < .05 vs vehicle treated). In the flo...

Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmun…

Wang(C),Ming(B),Wu(X),Wu(T),Cai(S),Hu(P),Tan… EBioMedicine 2019-07-00

...Syk were impaired in SMS1 knockout B cells. Furthermore, SMS1 knockout mice showed reduced production and deposition of ...

Pathogenic fungus Microsporum canis activates the NLRP3 inflammasome.

Mao(L),Zhang(L),Li(H),Chen(W),Wang(H),Wu(S),… Infect Immun 2014-02-00

...Syk, Dectin-1, and Card9 were found to be involved in M. canis-induced IL-1β secretion via regulation of pro-IL-1β trans...

HangAmDan-B, an ethnomedicinal herbal mixture, suppresses inflammatory response…

Yu(T),Moh(SH),Kim(SB),Yang(Y),Kim(E),Lee(YW)… J Med Food 2013-01-00

HangAmDan-B (HAD-B) is a powdered mixture of eight ethnopharmacologically characterized folk medicines that is prescribe...

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