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Development of a metastatic fluorescent Lewis Lung carcinoma mouse model: ident…

Rask(L),Fregil(M),Høgdall(E),Mitchelmore(C),… Gene 2013-03-15

...SYK). A modest decrease in Drosha and Dicer mRNA levels was accompanied by significant downregulation of ten microRNAs, ...

RASSF1A Promoter Methylation Levels Positively Correlate with Estrogen Receptor…

Kajabova(V),Smolkova(B),Zmetakova(I),Sebova(… Transl Oncol 2013-06-00

...SYK) genes was detected in the tumors of 124, 19, 15, 15, and 6 patients with mean levels of 48.45%, 3.81%, 2.36%, 27.55...

Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signali…

Courtney(AH),Bennett(NR),Zwick(DB),Hudon(J),… ACS Chem Biol 2014-01-17

...Syk), they also promote BCR endocytosis, indicating that inhibitory antigens can be internalized. Together, our observat...

Differential regulation of marginal zone and follicular B cell responses by CD8…

Uhde(M),Kuehl(S),Richardt(U),Fleischer(B),Os… Int Immunol 2013-09-00

...SYK and ERK1/2 resulting in reduced numbers of proliferating cells in all CD83tg B cell subsets. Moreover, CD83tg follic...

Multidimensional single-cell analysis of BCR signaling reveals proximal activat…

Palomba(ML),Piersanti(K),Ziegler(CG),Decker(… PLoS One 2014-00-00

...SYK, pBTK) and distal (pPLCγ2, pBLNK, ppERK) phosphoresponses. PLSR identified the relationship between upstream tyrosin...

Alterations of Fc gamma receptor I and Toll-like receptor 4 mediate the antiinf…

Li(YN),Qin(XJ),Kuang(F),Wu(R),Duan(XL),Ju(G)… J Neurosci Res 2008-12-00

...Syk, as well as the increased production of the effector cytokines, interleukin (IL)-10 and IL-4. Interestingly, after t...

Analysis of FcgammaRIIA cytoplasmic tail requirements in signaling for serotoni…

Daniels(AB),Worth(RG),Dickstein(RJ),Dickstei… Scand J Immunol 2010-04-00

...Syk with piceatannol blocked phagocytosis as expected, it did not inhibit serotonin secretion. Additionally, inhibition ...

Assessing the role of Asp 194 in the transmembrane domains of the α-chain of th…

Rashid(A),Iodice(MW),Carroll(KM),Housden(JE)… Mol Immunol 2010-00-00

...Syk kinase while a non-polar substitution (D194L) gave rise to cell surface expression of the mutated receptor subunit b...

Response of adult mouse uterus to early disruption of estrogen receptor-alpha s…

Simmons(CD),Pabona(JM),Zeng(Z),Velarde(MC),G… J Endocrinol 2010-05-00

...Syk), with loss of Klf9, alone or in concert with DES. Our data support a molecular network between KLF9 and ESR1 in the...

Conventional dendritic cells mount a type I IFN response against Candida spp. r…

Bourgeois(C),Majer(O),Frohner(IE),Lesiak-Mar… J Immunol 2011-03-01

...Syk family kinase inhibitors and strictly requires completion of phagocytosis as well as phagosomal maturation. Striking...

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