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Tyro3, Axl, and Mertk receptors differentially participate in platelet activati…

Zhou(J),Yang(A),Wang(Y),Chen(F),Zhao(Z),Davr… Cell Commun Signal 2018-00-12

...Syk) and phospholipase C-γ2 (PLCγ2), was decreased in Axl-/- and Tyro3-/- platelets, but not in Mertk-/- platelets. Whil...

Utility of mast cell P815 for evaluating FcεRI-dependent and FcεRI-independent …

Misawa(R),Takemoto(K),Iji(M),Hao(L),Koresawa… Allergol Immunopathol (Madr) 2025-00-00

...Syk), Fyn, and Bruton tyrosine kinase (Btk), which are involved in degranulation, was upregulated. FcεRI has three subun...

P-Rex1 controls phagocytosis and the killing of bacteria by murine neutrophils …

Islam(P),Chu(JY),Chetwynd(SA),Walker(R),Hawk… Front Immunol 2025-00-00

...Syk. Recently identified adaptor functions of P-Rex1 in GPCR trafficking and glucose uptake do not seem to underlie its ...

Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated h…

Berger(M),Raslan(Z),Aburima(A),Magwenzi(S),W… Haematologica 2020-00-00

...Syk and protein kinase C. The effects of oxLDL on platelet function and cAMP signaling were blocked by pharmacological i...

Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossre…

Roesner(LM),Ernst(M),Chen(W),Begemann(G),Kie… Sci Rep 2019-00-01

...Syk kinase function was performed to investigate downstream signaling, which led to diminished hTrx responses. In our ex...

TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism…

Singh(RK),Haka(AS),Asmal(A),Barbosa-Lorenzi(… Arterioscler Thromb Vasc Biol 2020-00-00

...SYK (spleen tyrosine kinase), PI3K (phosphoinositide 3-kinase), and Akt in agLDL catabolism using the lysosomal synapse....

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic act…

Oh(EB),Kong(YJ),Kim(T),Jang(J),Yu(H),Park(JW… Sci Rep 2025-10-16

...Syk), linker for the activation of T cells (LAT), vav guanine nucleotide exchange factor 1 (Vav1), and Bruton tyrosine k...

Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmun…

Wang(C),Ming(B),Wu(X),Wu(T),Cai(S),Hu(P),Tan… EBioMedicine 2019-07-00

...Syk were impaired in SMS1 knockout B cells. Furthermore, SMS1 knockout mice showed reduced production and deposition of ...

Signaling Cross-Talk between MHC Class II Molecular Conformers in Resting Murin…

Drake(JR) Immunohorizons 2019-00-18

...Syk protein tyrosine kinase activity. In contrast, multimerized forms of two different anti-I-Ak mAbs that bind both M1-...

The Inflammatory Nexus: Unraveling Shared Pathways and Promising Treatments in …

Russo(AP),Pastorello(Y),Dénes(L),Brînzaniuc(… Int J Mol Sci 2025-06-27

...SYK), the mechanistic (or mammalian) target of rapamycin (mTOR), and the S100 calcium-binding protein B (S100B)/receptor...

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