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Comprehensive transcriptome profiling of the chicken bursa infected with the no…

Xiong(H),Wu(J),Wang(S),Zhang(J),Zhang(W),Wan… Poult Sci 2025-12-12

...SYK) were significantly down-regulated, indicating impaired humoral immunity. Competing endogenous RNA (ceRNA) network a...

Platelet membrane-coated nanoparticles inhibit platelet activation and neutroph…

Li(X),Tang(Z),Kuang(L),Wu(Y),Huang(X) J Transl Med 2025-07-25

...Syk phosphorylation in vitro. Furthermore, we evaluated the therapeutic effects of PNPs on acute lung inflammatory respo...

CCNE1 amplification is associated with poor prognosis in patients with triple n…

Zhao(ZM),Yost(SE),Hutchinson(KE),Li(SM),Yuan… BMC Cancer 2019-01-21

...SYK) were differentially expressed in recurrent TNBCs, and were also overexpressed in TCGA and METABRIC. CCNE1 and TPX2 ...

Cancer cell-derived immunoglobulin G activates platelets by binding to platelet…

Miao(S),Shu(D),Zhu(Y),Lu(M),Zhang(Q),Pei(Y),… Cell Death Dis 2019-00-28

...syk, PLCγ2. The interaction between cancer cell-derived IgG and platelet FcγRIIa was analyzed by co-immunoprecipitation....

Macrophage Trem2 deficiency aggravates aging-induced vascular remodeling by act…

Chen(Y),Zeng(Z),Wei(Z),Zhan(Y),Wu(L),Zhu(X),… Mol Biomed 2025-12-29

...Syk-Sp1-SLC25A51 pathway to enhance mitochondrial nicotinamide adenine dinucleotide (NAD)⁺ transport. This triggered met...

Genome-wide discovery of somatic coding and noncoding mutations in pediatric en…

Grande(BM),Gerhard(DS),Jiang(A),Griner(NB),A… Blood 2019-00-21

...Syk, and Src family kinases among these patients.

Exposure to silver nanoparticles primes mast cells for enhanced activation thro…

Alsaleh(NB),Mendoza(RP),Brown(JM) Toxicol Appl Pharmacol 2019-00-01

...Syk, PLCγ and LAT. Our findings indicate that pre-exposure to AgNPs exacerbates mast cell allergen-mediated phosphorylat...

Dexamethasone induced Dectin-1 activation enhances NLRP3 inflammasome activatio…

Koerber(RM),Oberbeck(S),Kotthoff(P),Daecke(S… Front Immunol 2025-00-00

...Syk-inhibitors led to diminished inflammasome activation as well as to less pyroptosis and apoptosis in response to β -g...

Reticulated platelets in coronary artery disease: a multidimensional approach u…

Kirmes(K),Han(J),Klug(M),Bloxham(CJ),Babyak(… Eur Heart J 2025-12-01

...SYK, and elevated reactive oxygen species production. RPs showed increased aggregation, spreading and greater recruitmen...

Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits plate…

Nayak(MK),Dhanesha(N),Doddapattar(P),Rodrigu… Blood Adv 2018-00-14

...Syk and PLCγ2 in response to collagen or convulxin in human and mouse platelets (P < .05 vs vehicle treated). In the flo...

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