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Modulation of inflammasome components in patients with heart failure using or...

Herrera-Martínez(AD),Hermán-Sánchez(N),G-G... Eur J Nutr 2026-02-03

...CTSL, IFI16, TLR8, PSXR7, CCR1, CHUCK, MAPK14, CDKN1B). We observed a significant downregulation of Nod-like receptors N...

Exploring the effects of tinzaparin and cisplatin on lung cancer cells in vitro.

Held(J),Schneider(MA),Martinez-Delgado(B),... Cancer Cell Int 2026-02-05

...CTSL (Cathepsin L) and HMOX1 (Heme Oxygenase 1) consistently altered by tinzaparin. CONCLUSION: Tinzaparin affects proli...

Cerebrospinal Fluid Proteome Reveals Dysregulation of Lysosomal and Axonal Pr...

Tang(H),Hu(J),Wu(Y),Gao(J),Wang(W),Zheng(X... J Proteome Res 2026-02-06

...CTSL, NPC2, and DNASE2, were significantly downregulated in the CSF of NS patients, and spNS patients presented a high C...

Fluorescence Polarization-Based High-Throughput Screening Assay for Inhibitor...

Guo(K),You(B),Zhou(W),Li(Y),Wang(Z),Zhang(... Bio Protoc 2025-07-20

...CTSL are under investigation for therapeutic applications. Current approaches for identifying CTSL inhibitors predominan...

UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation.

Chen(Y),Shi(Y),Zuo(X),Dong(X),Xiao(X),Chen... J Virol 2025-07-22

...CTSL, a critical protease required for SARS-CoV-2 entry via the endosomal pathway. Importantly, CTSL is not only essenti...

HO-1 Suppression by Co-Culture-Derived IL-6 Alleviates Ferritinophagy-Depende...

Zhang(M),Liu(S),Wang(Y),Shan(S),Cang(M) Cells 2025-08-10

...CTSL). Pathway enrichment analyses highlighted cell cycle regulation, TNF signaling, and ferroptosis. Gene ontology anal...

Cathepsin L-Activatable Fluorescent Probe for Real-Time Monitoring of Drug-Re...

Yu(Q),Chen(S),Yu(L),Xu(D),Yin(S) Chemistry 2025-08-01

...CTSL in chemoresistant malignancies, FR-DCO integrates a CTSL-specific dipeptide substrate (Phe-Arg, FR) with a dicyanoi...

The functional of cathepsin L in the ontogenesis and reproductive regulation ...

Zhang(JS),Li(J),Meng(JY),Tang(X),Saddique(... Sci Rep 2025-07-12

...CTSL has not been characterized in O. furnacalis. Our results showed that the 1,653 bp cloned length of OfCTSL contains ...

Mechanistic Perspectives on Radiation-Induced Skin Injury and the Protective ...

Huang(B),Chen(G),Yan(T),Ou(X),Yang(L),He(T... J Inflamm Res 2025-00-00

...CTSL, were overexpressed, correlating with impaired wound healing. Proteomic analysis revealed that BBR modulated 684 pr...

Repurposing a detrimental antibody epitope as targeted therapeutics for sepsi...

Chen(WQ),Lou(L),Qiang(XL),Zhu(CS),Li(JH),C... Mil Med Res None

...Ctsl) mRNA upregulation and pCTS-L secretion from human immune cells, crucially without perturbing other HMGB1-induced c...

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