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Fas-associated factor 1 is a scaffold protein that promotes β-transducin repe...

Zhang(Long),Zhou(Fangfang),Li(Yihao),Drabs... J Biol Chem 2012-11-19

...FAF1-mediated β-catenin polyubiquitination and impaired FAF1 in antagonizing Wnt/β-catenin signaling. FAF1 was shown to ...

Fas-associated factor 1 as a regulator of olfactory axon guidance.

Cheng(Kai),Bai(Li),Belluscio(Leonardo) J Neurosci 2011-10-13

...FAF1), an apoptosis regulatory molecule, we can rewire axonal projections. Interestingly, FAF1 is highly expressed in th...

Hierarchical binding of cofactors to the AAA ATPase p97.

Hänzelmann(Petra),Buchberger(Alexander),Sc... Structure 2011-09-28

...FAF1)UBX domain in complex with the p97N domain reveals that the signature Phe-Pro-Arg motif known to be crucial for int...

Crystal structure of human FAF1 UBX domain reveals a novel FcisP touch-turn m...

Kang(Wonchull),Yang(Jin Kuk) Biochem Biophys Res Commun 2011-07-14

...FAF1, p47, SAKS1 and UBXD7. FAF1, a multi-functional tumor suppressor protein, binds to the N domain of p97/VCP through ...

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degr...

Zhang(Long),Zhou(Fangfang),van Laar(Theo),... Mol Biol Cell 2011-11-09

...FAF1) as a negative regulator of Wnt/β-catenin signaling. We found overexpression of FAF1 to strongly inhibit Wnt-induce...

FAF1, a gene that is disrupted in cleft palate and has conserved function in ...

Ghassibe-Sabbagh(Michella),Desmyter(Lauren... Am J Hum Genet 2011-03-29

...faf1 is highly expressed in zebrafish cartilages during embryogenesis. Knockdown of zebrafish faf1 leads to pharyngeal c...

Structure and interaction of ubiquitin-associated domain of human Fas-associa...

Song(Jinsue),Park(Joon Kyu),Lee(Jae-Jin),C... Protein Sci 2010-02-12

...FAF1 (hFAF1-UBA) and examined its interaction with ubiquitin and ubiquitin-like proteins using nuclear magnetic resonanc...

Fas-associated factor 1 is a negative regulator in capsaicin induced cancer c...

Ghosh(Amiya K),Basu(Sreyashi) Cancer Lett 2010-03-02

...FAF1); a TRPV1 associated protein. Moreover, using RNA interference with small inhibitory RNAs (siRNA) for FAF1 we obser...

Crystallization and preliminary X-ray crystallographic analysis of human FAF1...

Kang(Wonchull),Shin(Hwa Young),Yang(Jin Ku... Acta Crystallogr Sect F Str... 2010-03-08

...FAF1 in modulating p97/VCP activity related to proteasomal protein degradation, crystallographic analysis of the FAF1 UB...

Crystallization and preliminary X-ray crystallographic analysis of the N doma...

Shin(Hwa Young),Kang(Wonchull),Lee(Sang Yo... Acta Crystallogr Sect F Str... 2010-03-23

...FAF1, the p97/VCP N domain was crystallized in complex with the FAF1 UBX domain. X-ray data were collected to 2.60 A res...

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