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Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engage...

Liao(Z),Arkinson(C),Martin(A) Cell Rep 2026-06-23

...Faf1 was shown to enhance this activity during replisome disassembly by unknown mechanisms. Here, we employ an in vitro ...

The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradati...

Kracht(M),Kröning(A),van den Boom(J),Gahlo... Sci Adv 2026-03-06

...FAF1, FAF2, or UBXN7. Stimulation of proteasomal degradation was largely caused by an increase of p97 unfolding rates, c...

Prolonged Mild Sleep Restriction Changes Epigenome-Wide DNA Methylation in Pe...

Barragán(R),Dye(CK),Aggarwal(B),Jelic(S),C... Aging Dis 2026-03-21

...FAF1; p=2.25E-05), and cg03179866 (MMP12; p=2.78E-05). All but one (cg23738833) showed hypermethylation after SR vs AS. ...

Genotyping of an intensively monitored cohort of Bos indicus cattle in wester...

Miyunga(AA),Karani(BE),Njeru(R),Nangekhe(G... Vet Parasitol Reg Stud Reports 2026-04-00

...FAF1 gene. Disease caused by T. parva is of major economic importance in eastern to southern Africa and better control m...

FAF1 cofactor enhances UFD1/NPL4-p97 unfolding efficiency across ubiquitin ch...

Lemmon(AA),Lima(CD) bioRxiv 2026-08-03

...FAF1 and UFD1 throughout the unfolding process are consistent with AlphaFold models and recent reports suggesting that F...

Fatty acid composition and genetic associations in breast muscle of Kaijiang ...

Yang(Z),Ren(J),Wang(L),Li(L),Bai(L),Peng(D... Br Poult Sci 2026-08-24

...FAF1, SPAG16, FGF12, GPC1 and HK2 located near associated loci, with enrichment in metabolic pathways including carbohyd...

eRNAs modulate mRNA stability and translation efficiency to bridge transcript...

Kuklinkova(R),Benova(N),Anene(CA) RNA 2026-04-16

...FAF1 mRNA independently of transcription and impacts cell migration. These findings redefine the regulatory scope of eRN...

Genome-wide association study identifies FUT2 rs601338 polymorphism linking i...

Chen(H),Bai(X),Liu(Z),Du(H),Chen(X),Wu(D),... Pancreatology 2025-09-00

...FAF1, MAMSTR, SGMS1, CSNK2A1, CEBPB, and CEBPG. Genetic colocalization and transcriptome-wide association studies (TWAS)...

Caspar modulates primordial germ cell fate both in an Oskar-dependent and Osk...

Das(S),Roy(AE),Kanika,Deshpande(G),Ratnapa... Biol Open 2025-07-15

...FAF1), promotes PGC formation/specification and maintains the PGC count by modulating both the Osk levels and centrosome...

SUMO-Enriched Proteome for Drosophila Innate Immune Response.

Handu(Mithila),Kaduskar(Bhagyashree),Ravin... G3 (Bethesda) 2016-04-06

...FAF1 ortholog that negatively regulates immune-deficient signaling, is SUMOylated at K551 and responds to treatment with...

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