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JAK2 pathogenic variants in ischemic stroke: low prevalence and pre-screening...

Zhao(J),Ge(S),Gao(S),Xue(L),Shi(Y),Lu(C),F... J Neurol 2026-02-07

...JAK2 V617F test results. 46 cases (0.4%, 46/10428) harbored the JAK2 V617F-exclusive mutation. Mutation carriers manifes...

Natural compounds as immune checkpoint inhibitors in melanoma: a systematic r...

Samieefar(S),Arasteh(O),Yeganeh Khorasanii... Naunyn Schmiedebergs Arch P... 2026-05-00

...JAK2/STAT3 and IFN-γ/STAT1 suppression. Emerging bioactive sources such as Polygonum minus and drimenol were identified ...

Centrosomal JAK2 Tyrosine Kinase Regulates Primary Cilia Length, Cell Prolife...

Karki(G),Boone(L),Klaiber(T),Lambert(T),Ki... FASEB J 2026-02-28

...JAK2 inhibition or CRISPR-mediated JAK2 knockout (KO) results in cilia elongation. Using a nocodazole washout assay, we ...

Exploring the Therapeutic Potential and Underlying Mechanism of Callerya spec...

Liu(D),Wei(W),Xue(J),Chen(T),Chen(J),Feng(... Curr Top Med Chem 2026-02-04

...JAK2, and IL7R as core targets, whose elevated expression correlated with an increased risk of AS. GO/KEGG analysis indi...

Headache and Papilledema Unmasking an Underlying Myeloproliferative Neoplasm:...

Hossain(S),Tawfiq(T) Cureus 2026-01-00

...JAK2-positive myeloproliferative neoplasm, for which cytoreductive therapy was initiated alongside anticoagulation. This...

Macrophage erythropoietin receptor signaling drives macrophage-myofibroblast ...

Wu(P),Jia(J),Jin(T),Sun(X),Luo(B),Wang(G),... Biochem Biophys Res Commun 2026-04-09

...JAK2/STAT3 signaling pathways, while the JAK2 inhibitor AG490 inhibited EPOR-mediated Smad3 activation. BMDMs from EPOR-...

Overall survival with momelotinib vs. best available therapy in patients with...

Palandri(F),Kapetanakis(V),Dobi(B),Breccia... Ann Hematol 2026-02-21

...JAK2/activin A receptor type 1 inhibitor, has demonstrated benefits in reducing anemia and improving symptoms and spleen...

MiR-135b-5p relieves sevoflurane-induced postoperative cognitive dysfunction ...

Guo(FH),Xie(T),Kang(JM),Liu(YH),Xu(HM) Brain Res Bull 2026-04-00

...JAK2 to suppress the JAK2-STAT3 pathway. However, little is currently known about how miR-135b-5p contributes to the dys...

Zuoguiyin modulates M2 macrophage polarization to inhibit glycolysis in esoph...

Wang(Y),Guo(J),Zhou(L),Yuan(J),Huang(R),Xi... J Ethnopharmacol 2026-05-10

...JAK2. This study elucidates the mechanism through which IL-4/JAK2/STAT6-mediated M2 macrophages promote glycolysis in ES...

Combination of artesunate and ruxolitinib suppresses T cell leukemia/lymphoma...

Yuan(Y),Li(Y),Li(J),Wang(S),Luo(F),Huang(C... Sci Rep 2026-02-11

...JAK2 and STAT5 but did not alter mRNA or protein expression of JAK2. The drugs had a stronger inhibitory effect on growt...

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