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Developmental lead exposure and lifespan alterations in epigenetic regulators...

Eid(Aseel),Bihaqi(Syed Waseem),Renehan(Wil... Alzheimers Dement (Amst) 2016-05-30

...MAT2A) and histone proteins (H3K9Ac, H3K4me2, H3K27me3).,Cerebral levels of DNMT1 and MeCP2 were significantly reduced i...

New insights on the role of epigenetic alterations in hepatocellular carcinom...

Frau(Maddalena),Feo(Claudio F),Feo(Frances... J Hepatocell Carcinoma 2016-08-10

...MAT2A genes in HCC result in decreased S-adenosylmethionine levels, global DNA hypomethylation, and deregulation of sign...

WITHDRAWN: Silencing of human methionine adenosyltransferase 1A expression by...

Li(Mei),Ou(Xiaopeng),Lee(Taunia D),Zeng(Yi... J Biol Chem 2015-12-02

...MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT). MAT1A is silenced in hepatocellular carcino...

5-Aza-2<-deoxycytidine induces hepatoma cell apoptosis via enhancing methioni...

Liu(Wei-Jun),Ren(Jian-Guo),Li(Ting),Yu(Guo... Asian Pac J Cancer Prev 2015-01-21

...MAT2A mRNA and protein expression was significantly reduced in Huh7 cells treated with 5-Aza-CdR, while SAMe production ...

Markers of hepatic regeneration associated with surgical attenuation of conge...

Tivers(Michael S),Lipscomb(Victoria J),Smi... Vet J 2015-04-09

...MAT2A; P = 0.002) mRNA expression following partial CPSS attenuation. Dogs with complete attenuation had significantly g...

In vitro characterization of uptake mechanism of L-[methyl-(3)H]-methionine i...

Kuang(Yu),Wang(Fangjing),Corn(David J),Tia... Mol Imaging Biol 2015-03-12

...MAT2A gene expression. Control or SAM-treated WCH17 cells were pulsed with L-[methyl-(3)H]-Met for 5 min and chased with...

MAT2A mutations predispose individuals to thoracic aortic aneurysms.

Guo(Dong-chuan),Gong(Limin),Regalado(Ellen... Am J Hum Genet 2015-03-14

...mat2aa in zebrafish via morpholino oligomers disrupted cardiovascular development. Co-transfected wild-type human MAT2A ...

Role of methionine adenosyltransferase α2 and β phosphorylation and stabiliza...

Ramani(Komal),Donoyan(Shant),Tomasi(Maria ... J Cell Physiol 2015-04-10

...MAT2A and MAT2B (encoding MATα2 and MATβ proteins respectively), are required for HSC activation and loss of MAT2A trans...

Metabolic aspects of epigenome: coupling of S-adenosylmethionine synthesis an...

Igarashi(Kazuhiko),Katoh(Yasutake) Subcell Biochem 2014-02-18

...MAT2A), have been identified in mammals. MATII consists of α2 catalytic subunit encoded by MAT2A and β regulatory subuni...

Overexpression of methionine adenosyltransferase II alpha (MAT2A) in gastric ...

Zhang(Tao),Zheng(Zhichao),Liu(Yanqing),Zha... Acta Histochem 2014-08-12

...MAT2A expression level was significantly decreased in the transfected cells with MAT2A specific shRNA expression plasmid...

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