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Early thyroid hormone-induced gene expression changes in N2a-β neuroblastoma ...

Bedó(Gabriela),Pascual(Angel),Aranda(Ana) J Mol Neurosci 2012-04-24

...RalGDS was greatly up-regulated after 3-h treatment but not 24 h after. The results suggest an early involvement of thes...

RASSF1A methylation is predictive of poor prognosis in female breast cancer i...

Buhmeida(Abdelbaset),Merdad(Adnan),Al-Magh... Anticancer Res 2011-10-18

...RalGDS/AF-6) domain family member 1 isoform a (RASSF1A), hypermethylated in cancer 1 (HIC1), cyclin-dependent kinase inh...

The human Rgr oncogene is overexpressed in T-cell malignancies and induces tr...

Osei-Sarfo(K),Martello(L),Ibrahim(S),Pelli... Oncogene 2011-10-13

...RalGDS-related (Rgr) oncogene in a DMBA (7,12-dimethylbenz[α]anthracene)-induced rabbit squamous cell carcinoma and its ...

Biomarkers downstream of RAS: a search for robust transcriptional targets.

Györffy(Balazs),Schäfer(Reinhold) Curr Cancer Drug Targets 2011-05-19

...RalGDS/Ral pathway and other downstream pathways. Mutations in RAS lock the protein in its active form. Chronic activati...

Vibrational Stark effect spectroscopy at the interface of Ras and Rap1A bound...

Stafford(Amy J),Ensign(Daniel L),Webb(Laur... J Phys Chem B 2011-03-03

...RalGDS that direct the specificity of RalGDS binding to its in vivo binding partner, Rap1A, through an electrostatic mec...

RalGDS family members couple Ras to Ral signalling and that's not all.

Ferro(Elisa),Trabalzini(Lorenza) Cell Signal 2011-02-22

...RalGDS family, RalGDS, RGL, RGL2/Rlf and RGL3, can interact with activated Ras through their Ras Binding Domain (RBD), b...

Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial...

Kim(Kwang Soo),Park(Ji-Young),Jou(Ilo),Par... J Biol Chem 2010-08-12

...RalGDS-beta-arrestin complexes. Immuno-EM analysis revealed that alpha-synuclein was localized close to WPBs. These find...

The GTPase RalA regulates different steps of the secretory process in pancrea...

Ljubicic(Sanda),Bezzi(Paola),Vitale(Nicola... PLoS One 2010-04-26

...RalGDS and to be severely hampered upon silencing of this GDP/GTP exchange factor. Accordingly, INS-1E cells lacking Ral...

The small GTPase Ral couples the angiotensin II type 1 receptor to the activa...

Godin(Christina M),Ferreira(Lucimar T),Dal... Mol Pharmacol 2010-03-19

...RalGDS), and requires the beta-arrestin-dependent plasma membrane translocation of RalGDS. G alpha(q/11) small interferi...

Herpesviruses: hijacking the Ras signaling pathway.

Filippakis(Harilaos),Spandidos(Demetrios A... Biochim Biophys Acta 2010-07-27

...RALGDS) to regulate a cascade of events ranging from cell proliferation and survival to apoptosis and cellular death. In...

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