Yang(Q),Chen(J),Li(L),Chen(Z),Li(R),Zheng(... Int Immunopharmacol 2026-04-01

...ROCK2) inhibitor KD025 has been approved by FDA for treating chronic graft-versus-host disease (cGVHD) recently. ROCK2 i...

Hiebner(DW),Patil(S),Kenny(M),Baumann(J),M... Blood Adv 2026-05-26

...ROCK2) and myosin regulatory light chain 9 (MYL9) in adherent platelets, consistent with PAR>Gα13>RhoA signaling. Thromb...

Bai(Y),Ali(MM),van Dinther(M),Ten Dijke(P)... Cell Commun Signal 2026-02-07

...ROCK2 exhibit distinct subcellular localizations, and that SMAD3 interacts with ROCK1, but not with ROCK2. ROCK2 inhibit...

Wang(Y),Wu(Z),Han(Z),Li(Z),Zhang(T),Li(L) J Pharm Biomed Anal 2026-10-15

...ROCK2, Belm exhibits unique advantages in the treatment of hormone-dependent/refractory cGVHD. However, impurity control...

Sun(P),Wang(C),Li(W) Trends Pharmacol Sci 2026-06-00

Hu et al. identifies that Rho-associated coiled-coil containing kinase 2 (ROCK2) upregulation in sinusoidal endothelial ...

Cao(S),Shah(VH) Cell 2026-04-30

Hu et al identify ROCK2 in liver sinusoidal endothelial cells as a key factor in liver fibrosis. Through single-cell ana...

Chen(X),Zhou(L),Zhu(C),Sun(Z) Int J Mol Sci 2026-04-21

...ROCK2 were screened as hub targets. Bioinformatic analyses suggested that these targets were mainly associated with the ...

Pinheiro(PSM),Silva Franco(L),Pillpe-Meza(... ACS Bio Med Chem Au 2026-04-15

Rho-associated coiled-coil containing kinases (ROCK1 and ROCK2) are central regulators of actin cytoskeleton organizatio...

Wang(L),Zhao(F),Sun(Y),Liu(J),Wang(J),Wang... Am J Transl Res None

...ROCK2 signaling pathway and interacts with ACTB, thereby modulating cytoskeletal remodeling and promoting pseudopodia fo...

Liang(X),Li(D),Ji(R),Zhang(X),Wang(X),Zhan... Expert Opin Biol Ther 2026-05-00

...ROCK2 inhibitors), and the integration of patient-reported outcomes and functional measures into routine evaluation. The...