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SENP1 promotes p27kip1 nuclear export though enhanced SUMOylation in cholangi...

Jiang(K),Yang(W),Huang(J),Tan(X),Liu(Y),Tu... Int J Mol Med 2025-09-00

...SUMO1 precursors and deSUMOylating cytoplasmic substrates. SENP1 exhibited increased expression levels in CCA specimens ...

Tumor suppressor OSR1 is modified by SUMO1 and regulates the Wnt/β-catenin si...

Lin(X),Liu(Y),Lai(Z),Wang(X),Cui(Y),Weng(S... Exp Cell Res 2025-08-01

...SUMO1-modified OSR1 in HCC. Up-regulated co-expression of SUMO1-OSR1 was observed in the HepG2 cells. Through the cytolo...

Impact of Post-Translational Succination on Small Ubiquitin-Like Modifier 1 S...

Groignet(L),Dellemme(D),Duez(Q),Fizazi(A),... ACS Pharmacol Transl Sci 2025-08-08

SUMO1 (small ubiquitin-like modifier 1) is a key protein involved in the post-translational modification of a wide range...

A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimi...

Sommer(Stefanie),Ritterhoff(Tobias),Melchi... Chembiochem 2016-02-08

...SUMO1 as a structural analogue of the Ubc9∼SUMO1 thioester intermediate, by introducing a triazole linkage by biorthogon...

Association between cell cycle gene transcription and tumor size in oral squa...

Diniz(Marina Gonçalves),Silva(Jeane de Fat... Tumour Biol 2016-04-26

...SUMO1, KPNA2, MAD2L2, CCNG2, E2F4, NBN, CUL2, PCNA, TFDP1, KNTC1, and ATR. Ki-67 labeling index was similar in both tumo...

HIF-1α SUMOylation affects the stability and transcriptional activity of HIF-...

Han(Xiao),Wang(Xin-Ling),Li(Qin),Dong(Xiao... Graefes Arch Clin Exp Ophth... 2016-03-29

...SUMO1 ~ 4, Cbx4, PIASy, HIF-1α, GLUT1, and VEGFA were detected in the mRNA and protein levels by RT-PCR and Western blot...

SUMO modification of Akt regulates global SUMOylation and substrate SUMOylati...

Lin(C H),Liu(S Y),Lee(E H Y) Oncogene 2016-07-26

...SUMO1 at Thr76. Ubc9 phosphorylation at Thr35 promotes Ubc9 thioester bond formation and SUMO1 phosphorylation at Thr76 ...

Functional Proteomics Study Reveals SUMOylation of TFII-I is Involved in Live...

Tu(Jun),Chen(Yalan),Cai(Lili),Xu(Changming... J Proteome Res 2016-03-15

...SUMO1-modified proteins that were not present in the control samples. These proteins were enriched in gene expression pr...

Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma develop...

Deng(Rong),Zhao(Xian),Qu(YingYing),Chen(Ch... Oncotarget 2016-01-29

...SUMO1 at lysine residue 590 (K590) in its C-terminus, which is reduced by SUMO1-specific protease SENP1. Analysis of wil...

SUMO1 Affects Synaptic Function, Spine Density and Memory.

Matsuzaki(Shinsuke),Lee(Linda),Knock(Erin)... Sci Rep 2016-03-25

Small ubiquitin-like modifier-1 (SUMO1) plays a number of roles in cellular events and recent evidence has given momentu...

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