Literature Search

Wu(Y),Duan(L),Zhang(L),Wang(S),Yan(H),He(M),… Front Immunol 2026-00-00

...SYK pathway, PLCγ2-mediated Ca2+ signaling, PI3K-AKT-mTOR signaling, NF-κB activation and inflammatory regulatory pathwa...

Kubota(Y),Tsuboya(T),Murakami(M),Uehara(S),S… Front Immunol 2026-00-00

...Syk and PI3K inhibition substantially reduced EF-2001 phagocytosis. The inhibition of Syk, PI3K, and MAPKs hampered IL-1...

Wang(H),Yang(YH),Tang(JJ),Wang(XL),Liu(XY),W… Nat Commun 2026-08-14

...Syk/CARD9 axis governing Il1b transcription is defined, the epigenetic regulatory mechanisms remain elusive. Here, we id...

Rosell(R),González-Cao(M),Olmo-González(D),H… Ann Transl Med 2026-08-31

...Syk) signaling contributes to microglial activation and immune-related neurotoxicity during anti-programmed death 1 (PD-...

Moosavi(F),Hassani(B),Mortazavi(M),Peters(GJ… Cancers (Basel) 2026-06-16

...SYK. We have collected both computational studies and experimental reports, including functional assays, mechanistic stu...

Wade-Vallance(AK),Yang(Z),Libang(JB),Krishna… J Allergy Clin Immunol 2026-06-10

...Syk, whereas blockade of the PI3K subunit p110δ increased IgE cell frequencies independently of BCR ligation. The cytoki...

Liao(Y),Ren(Z),Zhou(J),Luo(H),Li(Y),Chen(D),… Adv Sci (Weinh) 2026-06-11

...Syk-Nox2 pathway, increasing phagosomal reactive oxygen species and membrane permeabilization to enable cytosolic antige...

Suk(K),Lee(WH),Zheng(LT) Histol Histopathol 2026-06-11

...SYK-BTK pathways-converge on key transcription factors such as NF-κB, AP-1, STAT1/3, and NFAT to shape glial inflammator...

Cho(S),Gabr(MT) Bioorg Med Chem Lett 2026-10-00

...SYK) signaling. Together, these findings support the presence of a previously unrecognized ectodomain interaction mode f...

Xu(F),Wang(M),Wang(B),Yang(J),Qian(X) Int J Mol Sci 2026-05-27

...Syk core regulatory axis, this review systematically elaborates the neutrophil recruitment cascade and intracellular sig...