Trenkle(Thomas),Hakim(Samer G),Jacobsen(Hans… Anticancer Res 2015-08-06

...VAV2 and VAV3 have been identified as important molecules in tumorigenesis, tumor growth and cell migration. In addition...

Menhofer(Magdalena H),Kubisch(Rebekka),Schre… PLoS One 2015-07-06

...Vav2 activation. At same conditions, EGF-receptor autophosphorylation, Akt and Erk as well as Rac1 are not affected. Fin...

Ménard(Ludovic),Parker(Peter J),Kermorgant(S… Nat Commun 2015-07-15

...Vav2 are required. Thus we describe a novel endosomal signalling mechanism whereby one signal output, Rac1, is stimulate...

Wan(Ya-Juan),Yang(Yin),Leng(Qian-Li),Lan(Bei… Cell Signal 2015-09-02

...Vav2 and Vav3 are ubiquitously distributed in almost all human tissues. All three Vav proteins contain conserved structu...

Zhang(Si-Cai),Gremer(Lothar),Heise(Henrike),… PLoS One 2015-03-04

...Vav2, Dbl, Tiam1, P-Rex1 and TrioN, and bound by the downstream effector Pak1. We found that dissociation of Rac1-GDP fr...

Huang(Chunyun),Sheng(Youyu),Jia(Jack),Chen(L… J Cancer Res Ther 2015-07-29

...VAV2, LCK, YES, PTCH2, downstream of tyrosine kinase [DOK], and KIT), module 16 (ELK3, p85beta, SHC, ZFYVE9, TGFBR1, TGF...

Schlegel(Nicolas),Waschke(Jens) Cell Tissue Res 2015-01-21

...Vav2 and stabilize the endothelial barrier via Rac1-mediated enforcement of adherens junctions and strengthening of the ...

Fabbiano(Salvatore),Menacho-Márquez(Mauricio… Mol Cell Biol 2015-01-16

...Vav2 exclusively in vSMCs leads to hypotension as well as the elimination of the hypertension induced by the systemic lo...

Li(Hsin-Pai),Huang(Hsin-Yi),Lai(Yi-Ru),Huang… Oncotarget 2015-08-06

...VAV2, WASL and ROCK1. Biochemical and functional assays provided supporting evidence that these 3 genes are the downstre...

Havel(L S),Kline(E R),Salgueiro(A M),Marcus(… Oncogene 2015-06-22

...VAV2, as having the greatest loss of phosphorylation owing to vimentin depletion. Since VAV2 serves as a GEF for the sma...