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Apoptosis signal-regulating kinase 1 controls the proapoptotic function of de...

Ko(Y G),Kang(Y S),Park(H),Seol(W),Kim(J),K... J Biol Chem 2001-12-04

...Daxx in the cytoplasm and inhibited the repressive activity of Daxx in transcription. In addition, Daxx was bound to the...

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facil...

Perlman(R),Schiemann(W P),Brooks(M W),Lodi... Nat Cell Biol 2001-09-13

...Daxx inhibit TGF-beta-induced apoptosis in mouse hepatocytes. Furthermore, Daxx is involved in mediating JNK activation ...

A kinase-independent function of Ask1 in caspase-independent cell death.

Charette(S J),Lambert(H),Landry(J) J Biol Chem 2001-11-01

...Daxx. Co-transfection of Ask1 and Daxx induced a caspase-independent cell-death process characterized at the morphologic...

CD95-induced JNK activation signals are transmitted by the death-inducing sig...

Hofmann(T G),Möller(A),Hehner(S P),Welsch(... Int J Cancer 2001-07-05

...Daxx impaired CD95-mediated apoptosis without affecting the JNK signal. DN forms of FADD, MKK4 and MKK7 completely inhib...

Evidence for separate ND10-binding and homo-oligomerization domains of Sp100.

Negorev(D),Ishov(A M),Maul(G G) J Cell Sci 2001-06-07

...Daxx, pRb, BLM and Sp100. In cells induced to overexpress Sp100, ND10 binding of Sp100 was saturable and excess Sp100 fo...

HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated m...

Genini(D),Sheeter(D),Rought(S),Zaunders(J ... FASEB J 2001-02-15

...DAXX, and RIP), was observed 72 h after infection. Our results suggest that HIV activates the p53 pathway, leading to cy...

New polymorphic microsatellite markers in the human MHC class II region.

Matsuzaka(Y),Makino(S),Nakajima(K),Tomizaw... Tissue Antigens 2001-03-29

...Daxx, BING1, RXRB and COL11A2). Twenty-two repeats were selected as polymorphic markers due to their high (average) numb...

Regulation of Pax3 transcriptional activity by SUMO-1-modified PML.

Lehembre(F),Müller(S),Pandolfi(P P),Dejean(A) Oncogene 2001-03-29

...Daxx to these nuclear structures and the relief of the repressive activity of Daxx. Conversely, lack of structurally int...

The Daxx enigma.

Michaelson(J S) Apoptosis 2001-04-26

...Daxx and its putative role have emerged without a unifying theme. While Daxx has been implicated in apoptosis, it remain...

The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discre...

Baumann(C T),Ma(H),Wolford(R),Reyes(J C),M... Mol Endocrinol 2001-09-20

...DAXX, and CREB-binding protein (CBP). Association with the ND10s is dependent on the AD1 of GRIP1, a region of the prote...

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