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Alteration of an essential NK cell signaling pathway by low doses of tributylti…

Aluoch(AO),Odman-Ghazi(SO),Whalen(MM) Toxicology 2006-07-25

...Syk, ZAP-70, Pyk2 and Src were examined, no significant activation was seen. These data imply that upstream activators o...

Heightened interferon-alpha/beta response causes myeloid cell dysfunction and p…

Peng(RH),Paek(E),Xia(CQ),Tennyson(N),Clare-S… Ann N Y Acad Sci 2006-10-00

...Syk kinase activity. We found, however, heightened responses to IFN-alpha/beta in NOD versus B6 as demonstrated by incre...

Molecular mechanisms involved in interleukin-4-induced human neutrophils: expre…

Ratthé(C),Pelletier(M),Chiasson(S),Girard(D) J Leukoc Biol 2007-05-00

...Syk, p38, Erk-1/2, JNK, Jak-1, Jak-2, STAT6, and STAT1 and that treatment of cells with the inhibitors piceatannol, SB20...

Scavenger receptor function of mouse Fcγ receptor III contributes to progressio…

Zhu(X),Ng(HP),Lai(YC),Craigo(JK),Nagilla(PS)… J Immunol 2014-09-01

...Syk phosphorylation. Collectively, our findings suggest scavenger receptor activity of CD16 may, in part, contribute to ...

A meta-analysis of somatic mutations from next generation sequencing of 241 mel…

Xia(J),Jia(P),Hutchinson(KE),Dahlman(KB),Joh… Mol Cancer Ther 2014-07-00

...SYK, and KDR), including five genes (RAC1, ADAMTS18, EPHA7, TAF1L, and NF1) with a recurrent mutation in at least two "p...

Systematic genomic identification of colorectal cancer genes delineating advanc…

Lee(H),Flaherty(P),Ji(HP) BMC Med Genomics 2013-12-05

...SYK, DDX5 and ADRA2C. These genetic features were identified robustly in bootstrap resampling analysis. We conducted an ...

A group of sequence-related sphingomonad enzymes catalyzes cleavage of β-aryl e…

Gall(DL),Ralph(J),Donohue(TJ),Noguera(DR) Environ Sci Technol 2014-10-21

...SYK-6 have conserved functions as β-etherases, catalyzing cleavage of each of the four dimeric α-keto-β-aryl ether-linke...

Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis …

Yu(T),Ahn(HM),Shen(T),Yoon(K),Jang(HJ),Lee(Y… J Ethnopharmacol 2011-10-11

...Syk), p38, and transforming growth factor β-activated kinase 1 (TAK1). Finally, orally administered Pa-EE clearly amelio...

NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts.

Allaeys(I),Marceau(F),Poubelle(PE) Arthritis Res Ther 2013-11-01

...Syk), but is independent of Src kinases. Simultaneously, MSU decreases phosphorylation of the protein kinases TOR (targe...

ZnO nanoparticles induced adjuvant effect via toll-like receptors and Src signa…

Roy(R),Kumar(D),Sharma(A),Gupta(P),Chaudhari… Toxicol Lett 2014-11-04

...Syk, IP3, p-PLC-γ and cAMP. Ca(2+) influx was significantly increased as well in the ZnO NPs/OVA group. These findings d...

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